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Title: Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures

Abstract

Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip.

Inventors:
; ; ; ; ;
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1177079
Patent Number(s):
8,993,327
Application Number:
10/408,294
Assignee:
UT-Battelle, LLC (Oak Ridge, TN) ORO
DOE Contract Number:
AC05-00OR22725
Resource Type:
Patent
Resource Relation:
Patent File Date: 2003 Apr 07
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 77 NANOSCIENCE AND NANOTECHNOLOGY

Citation Formats

McKnight, Timothy E, Melechko, Anatoli V, Griffin, Guy D, Guillorn, Michael A, Merkulov, Vladimir L, and Simpson, Michael L. Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures. United States: N. p., 2015. Web.
McKnight, Timothy E, Melechko, Anatoli V, Griffin, Guy D, Guillorn, Michael A, Merkulov, Vladimir L, & Simpson, Michael L. Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures. United States.
McKnight, Timothy E, Melechko, Anatoli V, Griffin, Guy D, Guillorn, Michael A, Merkulov, Vladimir L, and Simpson, Michael L. Tue . "Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures". United States. doi:. https://www.osti.gov/servlets/purl/1177079.
@article{osti_1177079,
title = {Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures},
author = {McKnight, Timothy E and Melechko, Anatoli V and Griffin, Guy D and Guillorn, Michael A and Merkulov, Vladimir L and Simpson, Michael L},
abstractNote = {Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 31 00:00:00 EDT 2015},
month = {Tue Mar 31 00:00:00 EDT 2015}
}

Patent:

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