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Title: Photoreactive synthetic regulator of protein function and methods of use thereof

Abstract

The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.

Inventors:
; ; ; ; ;
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1177034
Patent Number(s):
8,993,736
Application Number:
13/059,052
Assignee:
The Regents of the University of California (Oakland, CA) CHO
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2010 May 06
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Trauner, Dirk, Isacoff, Ehud Y, Kramer, Richard H, Banghart, Matthew R, Fortin, Doris L, and Mourot, Alexandre. Photoreactive synthetic regulator of protein function and methods of use thereof. United States: N. p., 2015. Web.
Trauner, Dirk, Isacoff, Ehud Y, Kramer, Richard H, Banghart, Matthew R, Fortin, Doris L, & Mourot, Alexandre. Photoreactive synthetic regulator of protein function and methods of use thereof. United States.
Trauner, Dirk, Isacoff, Ehud Y, Kramer, Richard H, Banghart, Matthew R, Fortin, Doris L, and Mourot, Alexandre. Tue . "Photoreactive synthetic regulator of protein function and methods of use thereof". United States. doi:. https://www.osti.gov/servlets/purl/1177034.
@article{osti_1177034,
title = {Photoreactive synthetic regulator of protein function and methods of use thereof},
author = {Trauner, Dirk and Isacoff, Ehud Y and Kramer, Richard H and Banghart, Matthew R and Fortin, Doris L and Mourot, Alexandre},
abstractNote = {The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 31 00:00:00 EDT 2015},
month = {Tue Mar 31 00:00:00 EDT 2015}
}

Patent:

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Works referenced in this record:

Biologically Active Molecules with a “Light Switch”
journal, July 2006

  • Mayer, Günter; Heckel, Alexander
  • Angewandte Chemie International Edition, Vol. 45, Issue 30, p. 4900-4921
  • DOI: 10.1002/anie.200600387

Blockage of squid axon potassium conductance by internal tetra-N-alkylammonium ions of various sizes
journal, May 1981