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Title: NMR and MRI apparatus and method

Abstract

Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. Additional signal to noise benefits are obtained by use of a low noise polarization coil, comprising litz wire or superconducting materials. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Inventors:
; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1176131
Patent Number(s):
7,187,169
Application Number:
10/980,984
Assignee:
The Regents of the University of California (Oakland, CA)
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Resource Relation:
Patent File Date: 2004 Nov 03
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 36 MATERIALS SCIENCE

Citation Formats

Clarke, John, Kelso, Nathan, Lee, SeungKyun, Moessle, Michael, Myers, Whittier, McDermott, Robert, ten Haken, Bernard, Pines, Alexander, and Trabesinger, Andreas. NMR and MRI apparatus and method. United States: N. p., 2007. Web.
Clarke, John, Kelso, Nathan, Lee, SeungKyun, Moessle, Michael, Myers, Whittier, McDermott, Robert, ten Haken, Bernard, Pines, Alexander, & Trabesinger, Andreas. NMR and MRI apparatus and method. United States.
Clarke, John, Kelso, Nathan, Lee, SeungKyun, Moessle, Michael, Myers, Whittier, McDermott, Robert, ten Haken, Bernard, Pines, Alexander, and Trabesinger, Andreas. 2007. "NMR and MRI apparatus and method". United States. https://www.osti.gov/servlets/purl/1176131.
@article{osti_1176131,
title = {NMR and MRI apparatus and method},
author = {Clarke, John and Kelso, Nathan and Lee, SeungKyun and Moessle, Michael and Myers, Whittier and McDermott, Robert and ten Haken, Bernard and Pines, Alexander and Trabesinger, Andreas},
abstractNote = {Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. Additional signal to noise benefits are obtained by use of a low noise polarization coil, comprising litz wire or superconducting materials. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.},
doi = {},
url = {https://www.osti.gov/biblio/1176131}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {3}
}

Works referenced in this record: