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The Dictyostelium Developmental cDNA Project: Generation and Analysis of Expressed Sequence Tags from the First-Finger Stage of Development
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Structure and Function of the B-Cell Antigen Receptor
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Differential signaling through the Ig-α and Ig-β components of the B cell antigen receptor
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Renaissance of cancer therapeutic antibodies
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Proteomics to study genes and genomes
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Sequence and polyadenylation site determination of the murine immunoglobulin γ2a membrane 3' untranslated region
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September 1989 |
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The internalization of the IgG2a antigen receptor does not require the association with Ig-α and Ig-β but the activation of protein tyrosine kinases does
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B Cell Development Is Arrested at the Immature B Cell Stage in Mice Carrying a Mutation in the Cytoplasmic Domain of Immunoglobulin β
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Antigen-specific identification and cloning of hybridomas with a fluorescence-activated cell sorter.
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April 1979 |
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Antigen Receptors on B Lymphocytes
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Signal Transduction by the Antigen Receptors of B and T Lymphocytes
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Differential mRNA stabilities affect mRNA levels in mutant mouse myeloma cells
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January 1991 |
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Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody: Molecular analysis of altered antibody specificity
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May 1994 |
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IgG production in hybridoma batch culture: kinetics of IgG mRNA, cytoplasmic-, secreted- and membrane-bound antibody levels
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October 1991 |
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The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line.
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April 1992 |
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B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties.
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Alternative poly(A) site selection in complex transcription units: means to an end?
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July 1997 |
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Application of flow cytometric measurement of surface IgG in kinetic analysis of monoclonal antibody synthesis and secretion by murine hybridoma cells
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journal
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July 1989 |
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Reconstitution of B Cell Antigen Receptor-induced Signaling Events in a Nonlymphoid Cell Line by Expressing the Syk Protein-tyrosine Kinase
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Optimizing antibody production in batch hybridoma cell culture
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May 1995 |
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Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism
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50 million years of chordate evolution: Seeking the origins of adaptive immunity
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Monoclonal antibodies to human estrogen receptor.
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September 1980 |
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Scaffolds for engineering novel binding sites in proteins
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Clinical trials of antibody therapy
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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
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February 1999 |
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Loss of Antibody Productivity During Long-Term Cultivation of a Hybridoma Cell Line in Low Serum and Serum-Free Media
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April 1990 |
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Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor.
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Genetic diversity of the human immunoglobulin heavy chain VH region
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Changes in abundance of IgG 2a mRNA in the nucleus and cytoplasm of a murine B-lymphoma before and after fusion to a myeloma cell
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May 1996 |
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Genomics, gene expression and DNA arrays
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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
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November 1998 |
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Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors
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Transcriptional and posttranscriptional control of immunoglobulin mRNA production during Blymphocyte development
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January 1986 |
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Molecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgM.
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journal
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Treatment of B-Cell Lymphoma with Monoclonal Anti-Idiotype Antibody
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March 1982 |
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Monoclonal antibodies to beta-adrenergic receptors: use in purification and molecular characterization of beta receptors.
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December 1980 |
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The 3′-Untranslated Region of Membrane Exon 2 from the γ2a Immunoglobulin Gene Contributes to Efficient Transcription Termination
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May 1995 |
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Cell-specific expression of secreted versus membrane forms of immunoglobulin gamma 2b mRNA involves selective use of alternate polyadenylation sites.
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journal
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October 1985 |
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A telomere-independent senescence mechanism is the sole barrier to Syrian hamster cell immortalization
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Aberrant Trafficking of the B Cell Receptor Ig-αβ Subunit in a B Lymphoma Cell Line
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August 2000 |
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Regulation of nuclear poly(A) addition controls the expression of immunoglobulin M secretory mRNA
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November 2001 |
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Alternative splicing of CD79a (Ig-αmb-1) and CD79b (Ig-βB29) RNA transcripts in human B cells
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journal
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June 1995 |
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Proteomics
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April 1998 |
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Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane-specific IgG2b mRNA in myeloma cells.
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journal
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May 1986 |
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Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner.
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journal
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November 1995 |
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An unsolved problem of the clonal selection theory and the model of an oligomeric B-cell antigen receptor
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journal
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August 2000 |
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The late pollen-specific actins in angiosperms
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June 1999 |
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Identification of the genes encoding the IgM-α and Ig-β components of the IgM antigen receptor complex by amino-terminal sequencing
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journal
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December 1990 |
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Continuous cultures of fused cells secreting antibody of predefined specificity
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journal
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August 1975 |
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Stability of the B cell antigen receptor complex
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April 2000 |
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Molecular components of the B-cell antigen receptor complex of the IgM class
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journal
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February 1990 |
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With the benefit of hindsight
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journal
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August 2000 |
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Immortalization of human embryonic fibroblasts by overexpression of c-myc and simian virus 40 large T antigen
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December 2001 |
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Genomic Instability and Telomerase Activity in Human Bronchial Epithelial Cells during Immortalization by Human Papillomavirus-16 E6 and E7 Genes
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journal
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August 1997 |
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Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex
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journal
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June 1996 |
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Human Keratinocytes That Express hTERT and Also Bypass a p16INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics
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journal
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February 2000 |
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Antibody engineering via genetic engineering of the mouse: XenoMouse strains are a vehicle for the facile generation of therapeutic human monoclonal antibodies
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journal
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December 1999 |
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Use of Monoclonal Antibodies for the Diagnosis and Treatment of Bladder Cancer
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journal
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June 1999 |
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Rapid Hybridoma Screening Method for the Identification of Monoclonal Antibodies to Low-Abundance Cytoplasmic Proteins
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journal
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November 1998 |
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Molecular cloning of the Ig-? subunit of the human B-cell antigen receptor complex
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journal
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July 1992 |
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Transcriptional regulation of the mu-delta heavy chain locus in normal murine B lymphocytes.
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journal
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August 1984 |
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The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion.
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November 1995 |
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Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development.
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July 1987 |
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Printing Proteins as Microarrays for High-Throughput Function Determination
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September 2000 |
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Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion
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July 1976 |
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Increased half-life of μ immunoglobulin mRNA during mouse B cell development increases its abundancy
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August 1990 |
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CH gene rearrangements in IgM-bearing B cells and in the normal splenic DNA component of hybridomas making different isotypes of antibody
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November 1980 |
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The B-cell antigen receptor complex
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journal
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June 1991 |
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B-lineage regulated polyadenylation occurs on weak poly(A) sites regardless of sequence composition at the cleavage and downstream regions
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journal
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December 1996 |
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Ig-α Cytoplasmic Truncation Renders Immature B Cells More Sensitive to Antigen Contact
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journal
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November 1999 |
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B Cell Progenitors Are Arrested in Maturation but Have Intact VDJ Recombination in the Absence of Ig-α and Ig-β
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July 2002 |
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Rapid Isolation of Monoclonal Antibodies. Monitoring Enzymes in the Phytochelatin Synthesis Pathway
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November 2001 |
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The metabolism of a poly(A) minus mRNA fraction in HeLa cells
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September 1974 |
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Igα: B all that you can B
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October 1999 |