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Title: Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen

Abstract

Bioelectronic devices for the detection of estrogen include a collection of eukaryotic cells which harbor a recombinant lux gene from a high temperature microorganism wherein the gene is operably linked with a heterologous promoter gene. A detectable light-emitting lux gene product is expressed in the presence of the estrogen and detected by the device.

Inventors:
; ; ; ;
Publication Date:
Research Org.:
UT-Battelle, LLC, Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175871
Patent Number(s):
7,090,992
Application Number:
11/152,138
Assignee:
UT-Battelle, LLC (Oak Ridge, TN) ORNL
DOE Contract Number:  
FG05-94ER61870
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Simpson, Michael L., Paulus, Michael J., Sayler, Gary S., Applegate, Bruce M., and Ripp, Steven A. Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen. United States: N. p., 2006. Web.
Simpson, Michael L., Paulus, Michael J., Sayler, Gary S., Applegate, Bruce M., & Ripp, Steven A. Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen. United States.
Simpson, Michael L., Paulus, Michael J., Sayler, Gary S., Applegate, Bruce M., and Ripp, Steven A. Tue . "Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen". United States. https://www.osti.gov/servlets/purl/1175871.
@article{osti_1175871,
title = {Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen},
author = {Simpson, Michael L. and Paulus, Michael J. and Sayler, Gary S. and Applegate, Bruce M. and Ripp, Steven A.},
abstractNote = {Bioelectronic devices for the detection of estrogen include a collection of eukaryotic cells which harbor a recombinant lux gene from a high temperature microorganism wherein the gene is operably linked with a heterologous promoter gene. A detectable light-emitting lux gene product is expressed in the presence of the estrogen and detected by the device.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2006},
month = {8}
}

Patent:

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