pH-sensitive methacrylic copolymers and the production thereof
Patent
·
OSTI ID:1175647
The present invention provides novel multi-functional methacrylic copolymers that exhibit cationic pH-sensitive behavior as well as good water solubility under acidic conditions. The copolymers are constructed from tertiary amine methacrylates and poly(ethylene glycol) containing methacrylates. The copolymers are useful as gene vectors, pharmaceutical carriers, and in protein separation applications.
- Research Organization:
- Iowa State Univ., Ames, IA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- W-7405-ENG-82
- Assignee:
- Iowa State University Research Foundation (Ames, IA)
- Patent Number(s):
- 6,998,456
- Application Number:
- 10/367,415
- OSTI ID:
- 1175647
- Country of Publication:
- United States
- Language:
- English
Synthesis of Controlled Structure Water-Soluble Diblock Copolymers via Oxyanionic Polymerization
|
journal | March 1999 |
Characterization, dynamic swelling behaviour and solute transport in cationic networks with applications to the development of swelling-controlled release systems
|
journal | January 1996 |
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