Cloning and expression of recombinant adhesive protein Mefp-1 of the blue mussel, Mytilus edulis

Silverman, Heather G.; Roberto, Francisco F.

Title: Cloning and expression of recombinant adhesive protein Mefp-1 of the blue mussel, Mytilus edulis

Patent · Tue Jan 17 00:00:00 EST 2006

OSTI ID:1175628

Silverman, Heather G.; Roberto, Francisco F.

The present invention comprises a Mytilus edulis cDNA sequenc having a nucleotide sequence that encodes for the Mytilus edulis foot protein-1 (Mefp-1), an example of a mollusk foot protein. Mefp-1 is an integral component of the blue mussels' adhesive protein complex, which allows the mussel to attach to objects underwater. The isolation, purification and sequencing of the Mefp-1 gene will allow researchers to produce Mefp-1 protein using genetic engineering techniques. The discovery of Mefp-1 gene sequence will also allow scientists to better understand how the blue mussel creates its waterproof adhesive protein complex.

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Research Organization:: Idaho National Laboratory (INL), Idaho Falls, ID (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC07-99JD13727

Assignee:: Battelle Energy Alliance, LLC (Idaho Falls, ID)

Patent Number(s):: 6,987,170

Application Number:: 10/915,161

OSTI ID:: 1175628

Country of Publication:: United States

Language:: English

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