Self assembling proteins

Yeates, Todd O.; Padilla, Jennifer; Colovos, Chris

Self assembling proteins

Patent · 29 June 2004

OSTI ID:1174921

Yeates, Todd O.; Padilla, Jennifer; Colovos, Chris

Novel fusion proteins capable of self-assembling into regular structures, as well as nucleic acids encoding the same, are provided. The subject fusion proteins comprise at least two oligomerization domains rigidly linked together, e.g. through an alpha helical linking group. Also provided are regular structures comprising a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of a variety of nanostructures, where such structures include: cages, shells, double-layer rings, two-dimensional layers, three-dimensional crystals, filaments, and tubes.

Research Organization:: The Regents of the University of California, Oakland, CA (United States)

Sponsoring Organization:: USDOE

Assignee:: University Of California, The Regents Of

Patent Number(s):: 6,756,039

Application Number:: 09/564,710

OSTI ID:: 1174921

Country of Publication:: United States

Language:: English

References (11)

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Supertetrahedral Sulfide Crystals with Giant Cavities and Channels Li, Hailian; Laine, Aaron; O'Keefe, M. Science, Vol. 283, Issue 5405, p. 1145-1147 https://doi.org/10.1126/science.283.5405.1145	journal	February 1999

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Self assembling proteins

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