Screening combinatorial arrays of inorganic materials with spectroscopy or microscopy

Schultz, Peter G.; Xiang, Xiaodong; Goldwasser, Isy

Screening combinatorial arrays of inorganic materials with spectroscopy or microscopy

Patent · 03 February 2004

OSTI ID:1174713

Schultz, Peter G.; Xiang, Xiaodong; Goldwasser, Isy

Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc. Once prepared, these materials can be screened for useful properties including, for example, electrical, thermal, mechanical, morphological, optical, magnetic, chemical, or other properties. Thus, the present invention provides methods for the parallel synthesis and analysis of novel materials having useful properties.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC03-76SF00098

Assignee:: Lawrence Berkeley National Laboratory (Berkeley, CA)

Patent Number(s):: 6,686,205

Application Number:: 09/728,202

OSTI ID:: 1174713

Country of Publication:: United States

Language:: English

References (140)

Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries Gallop, Mark A.; Barrett, Ronald W.; Dower, William J. Journal of Medicinal Chemistry, Vol. 37, Issue 9 https://doi.org/10.1021/jm00035a001	journal	April 1994
A fully programmable system for the study of catalytic gas reactions Gehrer, E.; Hayek, K. Journal of Physics E: Scientific Instruments, Vol. 18, Issue 10 https://doi.org/10.1088/0022-3735/18/10/008	journal	October 1985
Simultaneous, Sequential, and Reverse Sequential Techniques for the Preparation of Binary Silica-supported Sodium/Strontium Catalysts and the Effect of Carbon Tetrachloride on the Oxidative Coupling of Methane Voyatzis, R.; Moffat, J. B. Energy & Fuels, Vol. 8, Issue 5 https://doi.org/10.1021/ef00047a014	journal	September 1994
Optically active complexes of transition metals (RhI, RuII, CoII and NiII) with 2-aminocarbonylpyrrolidine ligands. Selective catalysts for hydrogenation of prochiral olefins Corma, A.; Iglesias, M.; del Pino, C. Journal of Organometallic Chemistry, Vol. 431, Issue 2 https://doi.org/10.1016/0022-328X(92)80121-D	journal	June 1992
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Tuerk, C.; Gold, L. Science, Vol. 249, Issue 4968 https://doi.org/10.1126/science.2200121	journal	August 1990
Sciencescope Stone, R. Science, Vol. 254, Issue 5038 https://doi.org/10.1126/science.254.5038.1575	journal	December 1991
Evaluation of peptide libraries: An iterative strategy to analyze the reactivity of peptide mixtures with antibodies Blake, James; Litzi-Davis, Leonora Bioconjugate Chemistry, Vol. 3, Issue 6 https://doi.org/10.1021/bc00018a008	journal	November 1992
Strategies for epitope analysis using peptide synthesis Geysen, H. Mario; Rodda, Stuart J.; Mason, Tom J. Journal of Immunological Methods, Vol. 102, Issue 2 https://doi.org/10.1016/0022-1759(87)90085-8	journal	September 1987
In situ infrared measurements during hot filament CVD of diamond in a rotating substrate reactor Morrison, Philip W.; Taweechokesupsin, Oranut; Kovach, Christopher S. Diamond and Related Materials, Vol. 5, Issue 3-5 https://doi.org/10.1016/0925-9635(95)00451-3	journal	April 1996
Role of structure and electronic interactions in the catalytic behavior of NiO-TiO2 system Rubinstein, A. Journal of Catalysis, Vol. 35, Issue 1 https://doi.org/10.1016/0021-9517(74)90186-9	journal	October 1974
Superconductivity at 93 K in a new mixed-phase Y-Ba-Cu-O compound system at ambient pressure Wu, M. K.; Ashburn, J. R.; Torng, C. J. Physical Review Letters, Vol. 58, Issue 9 https://doi.org/10.1103/PhysRevLett.58.908	journal	March 1987
Phage Display Smith, George P.; Petrenko, Valery A. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960065d	journal	April 1997
Statistical design of experiments for protein crystal growth and the use of a precrystallization assay Carter, Charles W.; Baldwin, Eric T.; Frick, Lloyd Journal of Crystal Growth, Vol. 90, Issue 1-3 https://doi.org/10.1016/0022-0248(88)90299-0	journal	July 1988
Preparation of Bifunctional Catalysts by Solid-State ION Exchange in Zeolites and Catalytic Tests Karge, H. G.; Zhang, Y.; Beyer, H. K. Studies in Surface Science and Catalysis https://doi.org/10.1016/S0167-2991(08)64015-X	book	January 1993
Introduction: Combinatorial Chemistry Szostak, Jack W. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr9700080	journal	April 1997
Synthesis of nanocomposites: Organoceramics Messersmith, Phillip B.; Stupp, Samuel I. Journal of Materials Research, Vol. 7, Issue 9 https://doi.org/10.1557/JMR.1992.2599	journal	September 1992
Ethanol to gasoline process: effect of variables, mechanism, and kinetics Costa, Enrique; Uguina, Angeles; Aguado, Jose Industrial & Engineering Chemistry Process Design and Development, Vol. 24, Issue 2 https://doi.org/10.1021/i200029a003	journal	April 1985
Guest Editorial Czarnik, Anthony W. Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar950256n	journal	January 1996
An Improved Single-Pellet Reactor to Study the Interaction of Kinetics with Mass Transfer Effects in Heterogeneous Catalysis Hegedus, L. Louis; Petersen, Eugene E. Industrial & Engineering Chemistry Fundamentals, Vol. 11, Issue 4 https://doi.org/10.1021/i160044a025	journal	November 1972
Crystallization and preliminary characterization of mitogillin, a ribosomal ribonuclease from Aspergillus restrictus Martinez, Sergio E.; Smith, Janet L. Journal of Molecular Biology, Vol. 218, Issue 3 https://doi.org/10.1016/0022-2836(91)90692-Y	journal	April 1991
Organic Synthesis on Soluble Polymer Supports: Liquid-Phase Methodologies Gravert, Dennis J.; Janda, Kim D. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960064l	journal	April 1997
Peptides on phage: a vast library of peptides for identifying ligands Cwirla, S. E.; Peters, E. A.; Barrett, R. W. Proceedings of the National Academy of Sciences, Vol. 87, Issue 16, p. 6378-6382 https://doi.org/10.1073/pnas.87.16.6378	journal	August 1990
Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Barbas, C. F.; Kang, A. S.; Lerner, R. A. Proceedings of the National Academy of Sciences, Vol. 88, Issue 18 https://doi.org/10.1073/pnas.88.18.7978	journal	September 1991
The thermal behavior of crystalline aluminosilicate catalysts Hickson, D. Journal of Catalysis, Vol. 10, Issue 1 https://doi.org/10.1016/0021-9517(68)90219-4	journal	January 1968
Two-dimensional crystallization of a bacterial surface protein on lipid vesicles under controlled conditions Paul, A.; Engelhardt, H.; Jakubowski, U. Biophysical Journal, Vol. 61, Issue 1 https://doi.org/10.1016/S0006-3495(92)81825-8	journal	January 1992
Lateral-Chain Methylation of Toluene over Boron and/or Zinc Modified Cesium-X Zeolite Archier, D.; Coudurier, G.; Naccache, C. Proceedings from the Ninth International Zeolite Conference https://doi.org/10.1016/B978-1-4832-8383-8.50147-1	book	January 1993
In Vitro Selection of Catalytic Polynucleotides Breaker, Ronald R. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960008k	journal	April 1997
A stable catalyst for heavy oil processing Ramirez de Agudelo, M. M.; Galarraga, C. The Chemical Engineering Journal, Vol. 46, Issue 2 https://doi.org/10.1016/0300-9467(91)80024-Q	journal	June 1991
Unattended, robotic drug-release testing of enterically coated aspirin Eckstein, R. J.; Owens, Grover D.; Baim, M. A. Analytical Chemistry, Vol. 58, Issue 11 https://doi.org/10.1021/ac00124a044	journal	August 1986
Intermetallics for permanent magnets Stadelmaier, H. H. IEEE Transactions on Magnetics, Vol. 29, Issue 6 https://doi.org/10.1109/20.280925	journal	November 1993
Improving the cooperation of co-catalysts by locating them on different units of a copolymer Hong, L.; Ruckenstein, E. Journal of Molecular Catalysis, Vol. 77, Issue 3 https://doi.org/10.1016/0304-5102(92)80206-V	journal	December 1992
The Measurement of Extinction Coefficients Using a New Infrared Micropulse Reactor Technique: Adsorption of CO on Silica-Supported Pt Sárkány, János; Gonzalez, Richard D. Applied Spectroscopy, Vol. 36, Issue 3 https://doi.org/10.1366/0003702824638412	journal	May 1982
A novel reactor system that permits the direct determination of deactivation kinetics for a heterogeneous catalyst Jossens, L. Journal of Catalysis, Vol. 73, Issue 2 https://doi.org/10.1016/0021-9517(82)90109-9	journal	February 1982
Searching for peptide ligands with an epitope library Scott, J.; Smith, G. Science, Vol. 249, Issue 4967 https://doi.org/10.1126/science.1696028	journal	July 1990
In situ study of catalysts Waugh, K. C. Applied Catalysis, Vol. 43, Issue 2 https://doi.org/10.1016/S0166-9834(00)82735-9	journal	January 1988
Light-directed, spatially addressable parallel chemical synthesis Fodor, S.; Read, J.; Pirrung, M. Science, Vol. 251, Issue 4995 https://doi.org/10.1126/science.1990438	journal	February 1991
Applications of raman spectroscopy to heterogeneous catalysis Spivey, James J.; Agarwal, Sanjay K.; Wachs, Israel E. Catalysis https://doi.org/10.1039/9781847553225-00102	book	May 1993
Multisample thermoluminescence reading Gasiot, J.; Castagne, M.; Fillard, J. P. Nuclear Instruments and Methods, Vol. 175, Issue 1 https://doi.org/10.1016/0029-554X(80)90267-0	journal	September 1980
DTA apparatus as a catalytic microreactor with on-line analysis of the products Rogers, D. E.; Parker, L. M. Applied Catalysis, Vol. 51, Issue 1 https://doi.org/10.1016/S0166-9834(00)80204-3	journal	June 1989
Crystallization of ribozymes and small RNA motifs by a sparse matrix approach. Doudna, J. A.; Grosshans, C.; Gooding, A. Proceedings of the National Academy of Sciences, Vol. 90, Issue 16 https://doi.org/10.1073/pnas.90.16.7829	journal	August 1993
Lessons from the Immune System: From Catalysis to Materials Science Hsieh-Wilson, Linda C.; Xiang, Xiao-Dong; Schultz, Peter G. Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar950247e	journal	January 1996
Characterization of highly dealuminated faujasite-type zeolites: ultrastable zeolite Y and ZSM-20 Miessner, Hans; Kosslick, Hendrik; Lohse, Ursula The Journal of Physical Chemistry, Vol. 97, Issue 38 https://doi.org/10.1021/j100140a034	journal	September 1993
A New High- T _c Oxide Superconductor without a Rare Earth Element Maeda, Hiroshi; Tanaka, Yoshiaki; Fukutomi, Masao Japanese Journal of Applied Physics, Vol. 27, Issue Part 2, No. 2 https://doi.org/10.1143/JJAP.27.L209	journal	February 1988
Simple method for the simultaneous evaluation of combustion and selective oxidation catalysts Ramdasi, Sudhakar S.; Kulkarni, Suresh Y.; Gokarn, Ashok N. Journal of Chemical Technology & Biotechnology, Vol. 57, Issue 2 https://doi.org/10.1002/jctb.280570203	journal	January 1993
Compositional Determination of rf Co-Sputtered Multicomponent Systems Hanak, J. J. Journal of Vacuum Science and Technology, Vol. 8, Issue 1 https://doi.org/10.1116/1.1316278	journal	January 1971
Possible highT c superconductivity in the Ba?La?Cu?O system Bednorz, J. G.; M�ller, K. A. Zeitschrift f�r Physik B Condensed Matter, Vol. 64, Issue 2 https://doi.org/10.1007/BF01303701	journal	June 1986
Thousandfold Change in Resistivity in Magnetoresistive La-Ca-Mn-O Films Jin, S.; Tiefel, T. H.; McCormack, M. Science, Vol. 264, Issue 5157 https://doi.org/10.1126/science.264.5157.413	journal	April 1994
A Combinatorial Method for Generating New Zeolite Frameworks Treacy, M. M. J.; Rao, S.; Rivin, I. Proceedings from the Ninth International Zeolite Conference https://doi.org/10.1016/B978-1-4832-8383-8.50044-1	book	January 1993
Integrated enzyme reactor/detector for the determination of multiple substrates by image analysis Martin, Glenn B.; Rechnitz, Garry A. Analytica Chimica Acta, Vol. 281, Issue 3 https://doi.org/10.1016/0003-2670(93)85015-C	journal	September 1993
Two approaches to the rapid screening of crystallization conditions McPherson, Alexander Journal of Crystal Growth, Vol. 122, Issue 1-4 https://doi.org/10.1016/0022-0248(92)90239-F	journal	August 1992
Metal-support bonds in supported metal catalysts Gates, B. C. https://doi.org/10.2172/6446860	report	January 1990
Combinatorial chemistry Terrett, Nick Drug Discovery Today, Vol. 1, Issue 9 https://doi.org/10.1016/1359-6446(96)87179-0	journal	September 1996
Two-dimensional crystallization technique for imaging macromolecules, with application to antigen–antibody–complement complexes Uzgiris, Egidijus E.; Kornberg, Roger D. Nature, Vol. 301, Issue 5896 https://doi.org/10.1038/301125a0	journal	January 1983
Characterization and deactivation of NiOThO2 catalysts Richardson, J. T.; Cullinane, M. B.; Frank, A. S. Applied Catalysis, Vol. 48, Issue 1 https://doi.org/10.1016/S0166-9834(00)80273-0	journal	March 1989
Dynamic measurements of the electrical conductivity of a non-metallic catalyst during adsorption and catalysis Farrell, F. J.; Nevell, T. G.; Hucknall, D. J. Journal of Physics E: Scientific Instruments, Vol. 12, Issue 12 https://doi.org/10.1088/0022-3735/12/12/015	journal	December 1979
Synthesis, Characterization, and Catalytic Properties of Metallo-Titanium Silicate Molecular Sieves with MEL Topology Reddy, J. S.; Kumar, R.; Csicsery, S. M. Journal of Catalysis, Vol. 145, Issue 1 https://doi.org/10.1006/jcat.1994.1009	journal	January 1994
Nucleic Acid Selection and the Challenge of Combinatorial Chemistry Osborne, Scott E.; Ellington, Andrew D. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960009c	journal	April 1997
Isomerization and hydrolysis reactions of important disaccharides over inorganic heterogeneous catalysts Shukla, Rajesh; Verykios, Xenophon E.; Mutharasan, Rajakkannu Carbohydrate Research, Vol. 143 https://doi.org/10.1016/S0008-6215(00)90699-2	journal	November 1985
Automated protein crystallization and a new crystal form of a subtilisin:eglin complex Kelders, Henk A.; Kalk, Kor H.; Gros, Piet "Protein Engineering, Design and Selection", Vol. 1, Issue 4 https://doi.org/10.1093/protein/1.4.301	journal	January 1987
Selective chemical catalysis by an antibody Pollack, S.; Jacobs, J.; Schultz, P. Science, Vol. 234, Issue 4783 https://doi.org/10.1126/science.3787262	journal	December 1986
Chemistry of High-Temperature Superconductors Sleight, A. W. Science, Vol. 242, Issue 4885 https://doi.org/10.1126/science.242.4885.1519	journal	December 1988
Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery Houghten, Richard A.; Pinilla, Clemencia; Blondelle, Sylvie E. Nature, Vol. 354, Issue 6348 https://doi.org/10.1038/354084a0	journal	November 1991
High-pressure study of the new Y-Ba-Cu-O superconducting compound system Hor, P. H.; Gao, L.; Meng, R. L. Physical Review Letters, Vol. 58, Issue 9 https://doi.org/10.1103/PhysRevLett.58.911	journal	March 1987
Electroluminescence in ZnS: Mn _x : Cu _y rf–Sputtered Films Hanak, J. J. Japanese Journal of Applied Physics, Vol. 13, Issue S1 https://doi.org/10.7567/JJAPS.2S1.809	journal	January 1974
The simultaneous multiple production of solution phase peptides; assessment of the geysen method of simultaneous peptide synthesis. Bray, Andrew M.; Joe Maeji, N.; Mario Geysen, H. Tetrahedron Letters, Vol. 31, Issue 40 https://doi.org/10.1016/S0040-4039(00)97966-8	journal	January 1990
Multiple-Component Condensation Strategies for Combinatorial Library Synthesis Armstrong, Robert W.; Combs, Andrew P.; Tempest, Paul A. Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar9502083	journal	January 1996
Calculation of composition of dilute cosputtered multicomponent films Hanak, J. J.; Bolker, B. F. T. Journal of Applied Physics, Vol. 44, Issue 11 https://doi.org/10.1063/1.1662105	journal	November 1973
Catalytic vapor phase hydroformylation of propylene over supported rhodium complexes Robinson, K. Journal of Catalysis, Vol. 15, Issue 3 https://doi.org/10.1016/0021-9517(69)90286-3	journal	November 1969
Magnetoresistance in Metallic Crystals of La _{1- x} Sr _x CoO ₃ Yamaguchi, Shinya; Taniguchi, Hirohisa; Takagi, Hidenori Journal of the Physical Society of Japan, Vol. 64, Issue 6 https://doi.org/10.1143/jpsj.64.1885	journal	June 1995
Magnetic compounds wtth perovskite structure III. ferromagnetic compounds of cobalt Jonker, G. H.; Van Santen, J. H. Physica, Vol. 19, Issue 1-12 https://doi.org/10.1016/S0031-8914(53)80011-X	journal	January 1953
Isomerization of n-butene to isobutene *1I. Selection of catalyst by group screening Choudhary, V. Journal of Catalysis, Vol. 23, Issue 1 https://doi.org/10.1016/0021-9517(71)90024-8	journal	October 1971
Spatially resolved characterization of HgCdTe materials and devices by scanning laser microscopy Bajaj, J.; Tennant, W. E.; Zucca, R. Semiconductor Science and Technology, Vol. 8, Issue 6S https://doi.org/10.1088/0268-1242/8/6S/008	journal	June 1993
The study of the copolymerization of styrene and acrylonitrile to high conversion. application of low conversion reactivity ratios Hill, D. J. T.; Lang, A. P.; O'Donnell, J. H. European Polymer Journal, Vol. 27, Issue 8 https://doi.org/10.1016/0014-3057(91)90005-9	journal	January 1991
A design for a combined infrared cell/differential single-pass reactor Vannice, M. A.; Moon, S. H.; Twu, C. C. Journal of Physics E: Scientific Instruments, Vol. 12, Issue 9 https://doi.org/10.1088/0022-3735/12/9/016	journal	September 1979
The application of semi-conductivity measurements in the study of catalysis on copper oxide Gray, T. J. Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, Vol. 197, Issue 1050, p. 314-320 https://doi.org/10.1098/rspa.1949.0066	journal	June 1949
Photochemical Preparation of a Film-Based Catalyst with Spatial Control Leasure, Robert M.; Moss, John A.; Meyer, Thomas J. Inorganic Chemistry, Vol. 33, Issue 7 https://doi.org/10.1021/ic00085a004	journal	March 1994
The “One-Bead-One-Compound” Combinatorial Library Method Lam, Kit S.; Lebl, Michal; Krchňák, Viktor Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr9600114	journal	April 1997
Silver, sodium halosodalites: class A sodalites Stein, Andreas; Ozin, Geoffrey A.; Macdonald, Peter M. Journal of the American Chemical Society, Vol. 114, Issue 13 https://doi.org/10.1021/ja00039a032	journal	June 1992
Combinatorial Organic Synthesis Using Parke-Davis's DIVERSOMER Method DeWitt, Sheila Hobbs; Czarnik, Anthony W. Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar950209v	journal	January 1996
The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library. Bunin, B. A.; Plunkett, M. J.; Ellman, J. A. Proceedings of the National Academy of Sciences, Vol. 91, Issue 11 https://doi.org/10.1073/pnas.91.11.4708	journal	May 1994
Isomerization of Meta-Xylene Over Pentasil-Type Microporous Gallosilicates Richter, M.; Kosslick, H.; Tuan, Vu Anh Berichte der Bunsengesellschaft für physikalische Chemie, Vol. 96, Issue 4 https://doi.org/10.1002/bbpc.19920960413	journal	April 1992
Surface reactions of alkanes and organometallic chemistry applied to the study of pure and bimetallic catalysts Coq, B.; Bittar, A.; Tazi, T. Journal of Molecular Catalysis, Vol. 55, Issue 1 https://doi.org/10.1016/0304-5102(89)80240-8	journal	November 1989
Structural Chemistry and the Local Charge Picture of Copper Oxide Superconductors Cava, R. J. Science, Vol. 247, Issue 4943 https://doi.org/10.1126/science.247.4943.656	journal	February 1990
Synchrony and the emergence of chaos in oscillations on supported catalysts Schüth, F.; Song, X.; Schmidt, L. D. The Journal of Chemical Physics, Vol. 92, Issue 1 https://doi.org/10.1063/1.458428	journal	January 1990
A simple-design high vacuum infrared cell for in situ studies of supported metal catalysts Moon, Sang H.; Windawi, Hassan; Katzer, James R. Industrial & Engineering Chemistry Fundamentals, Vol. 20, Issue 4 https://doi.org/10.1021/i100004a018	journal	November 1981
Solid-State Chemistry: A A Rediscovered Chemical Frontier DiSalvo, F. J. Science, Vol. 247, Issue 4943 https://doi.org/10.1126/science.247.4943.649	journal	February 1990
Studies on the Modified Claus Reaction Over Alkaline Faujasites by Simultaneous Infrared, Kinetics, and esr Measurements Karge, H. G.; Zhang, Y.; Trevizan De Suarez, S. Studies in Surface Science and Catalysis https://doi.org/10.1016/S0167-2991(09)61140-X	book	January 1984
Discovery of Sequence-Selective Peptide Binding by Synthetic Receptors Using Encoded Combinatorial Libraries Still, W. Clark Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar950166i	journal	January 1996
Radio‐Frequency‐Sputtered Films of β‐Tungsten Structure Compounds Hanak, J. J.; Gittleman, J. I.; Pellicane, J. P. Journal of Applied Physics, Vol. 41, Issue 12 https://doi.org/10.1063/1.1658570	journal	November 1970
A new type of synthetic peptide library for identifying ligand-binding activity Lam, Kit S.; Salmon, Sydney E.; Hersh, Evan M. Nature, Vol. 354, Issue 6348 https://doi.org/10.1038/354082a0	journal	November 1991
Selectivity over unifunctional multicomponent catalysts with non-uniform distribution of components Dadyburjor, Dady B. Industrial & Engineering Chemistry Fundamentals, Vol. 24, Issue 1 https://doi.org/10.1021/i100017a004	journal	February 1985
At the crossroads of chemistry and immunology: catalytic antibodies Lerner, R.; Benkovic, S.; Schultz, P. Science, Vol. 252, Issue 5006 https://doi.org/10.1126/science.2024118	journal	May 1991
Carbon monoxide hydrogenation over Fe/HZSM-5 catalysts. Effect of SiO2/Al2O3 zeolite ratio Calleja, G.; de Lucas, A.; van Grieken, R. Catalysis Letters, Vol. 18, Issue 1-2 https://doi.org/10.1007/BF00769499	journal	March 1993
Development of A Micro Hydroprocessing Test for Rapid Evaluation of Catalysts Sudhakar, C.; Mtshali, L. T.; Fritz, P. O. Studies in Surface Science and Catalysis https://doi.org/10.1016/S0167-2991(08)64461-4	book	January 1993
Antifertility and biocidal activities of organometallics of silicon, germanium, titanium and zirconium derived from 2-acetylthiophene thiosemicarbazone Singh, Devendra; Kumari, Anita; Singh, R. V. Applied Organometallic Chemistry, Vol. 7, Issue 4 https://doi.org/10.1002/aoc.590070408	journal	July 1993
Organometallics derived (Pd + Ln)/SiO2 catalysts for the reactions of synthesis gas conversion Nogin, Yu. N.; Chesnokov, N. V.; Kovalchuk, V. I. Catalysis Letters, Vol. 23, Issue 1-2 https://doi.org/10.1007/BF00812133	journal	March 1994
Strategy and Tactics in Combinatorial Organic Synthesis. Applications to Drug Discovery Gordon, E. M.; Gallop, M. A.; Patel, D. V. Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar950170u	journal	January 1996
Spatially Addressable Combinatorial Libraries Pirrung, Michael C. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960013o	journal	April 1997
Low temperature linear magnetic field sensor based on magnetoresistance of the perovskite oxide La–Sr–Co–O Mahendiran, R.; Raychaudhuri, A. K.; Chainani, A. Review of Scientific Instruments, Vol. 66, Issue 4 https://doi.org/10.1063/1.1146446	journal	April 1995
Generation and screening of an oligonucleotide-encoded synthetic peptide library. Needels, M. C.; Jones, D. G.; Tate, E. H. Proceedings of the National Academy of Sciences, Vol. 90, Issue 22 https://doi.org/10.1073/pnas.90.22.10700	journal	November 1993
H- and Cu- Forms of MFI Boralites with Enhanced Number of Skeletal Boron Atoms. Synthesis and Properties Kubelková, Ludmila; Jirka, Ivan; Vylita, Jan Studies in Surface Science and Catalysis https://doi.org/10.1016/S0167-2991(08)63641-1	book	January 1994
Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions Gordon, Eric M.; Barrett, Ronald W.; Dower, William J. Journal of Medicinal Chemistry, Vol. 37, Issue 10 https://doi.org/10.1021/jm00036a001	journal	May 1994
Design, Synthesis, and Evaluation of Small-Molecule Libraries Ellman, Jonathan A. Accounts of Chemical Research, Vol. 29, Issue 3 https://doi.org/10.1021/ar950190w	journal	January 1996
A surface spectroscopic study of molybdenum-alumina catalysts using x-ray photoelectron, ion-scattering, and Raman spectroscopies Zingg, D. S.; Makovsky, Leo E.; Tischer, R. E. The Journal of Physical Chemistry, Vol. 84, Issue 22 https://doi.org/10.1021/j100459a015	journal	October 1980
Zeolates: a coordination chemistry view of metal-ligand bonding in zeolite guest-host inclusion compounds Ozin, Geoffrey A.; Ozkar, Saim Chemistry of Materials, Vol. 4, Issue 3 https://doi.org/10.1021/cm00021a008	journal	May 1992
Microstructural Study of an Iron Silicate Catalyst by Electron Microscopy Csencsits, Roseann; Gronsky, Ronald ACS Symposium Series https://doi.org/10.1021/bk-1989-0411.ch033	book	October 1989
A Class of Cobalt Oxide Magnetoresistance Materials Discovered with Combinatorial Synthesis Brice o., G.; Chang, H.; Sun, X. Science, Vol. 270, Issue 5234 https://doi.org/10.1126/science.270.5234.273	journal	October 1995
Local gas sampling and surface hydrogen detection in catalysis on planar surfaces Ackelid, U.; Fogelberg, J.; Petersson, L-G Vacuum, Vol. 42, Issue 14 https://doi.org/10.1016/0042-207X(91)90553-U	journal	January 1991
Verfahren zur quantitativen Auswertung katalytischer Reaktionen: die Simultankomparations-Methode Bognár, János Microchimica Acta, Vol. 51, Issue 5-6 https://doi.org/10.1007/BF01217605	journal	September 1963
Complex synthetic chemical libraries indexed with molecular tags Ohlmeyer, M. H.; Swanson, R. N.; Dillard, L. W. Proceedings of the National Academy of Sciences, Vol. 90, Issue 23 https://doi.org/10.1073/pnas.90.23.10922	journal	December 1993
Effect of the Reaction Medium on the Metal Microstructure of Nickel-Zeolite Catalysts Davidova, N. P.; Valcheva, M. L.; Shopov, D. M. Metal Microstructures in Zeolites - Preparation-Properties-Applications, Proceedings of a Workshop https://doi.org/10.1016/S0167-2991(09)61014-4	book	January 1982
A Comparison of Some Catalytic Properties of Unsupported MOS2 and WS2 Catalysts Promoted by Group VIII Metals Vrinat, M.; Lacroix, M.; Breysse, M. Bulletin des Sociétés Chimiques Belges, Vol. 93, Issue 8-9 https://doi.org/10.1002/bscb.19840930811	journal	January 1984
Dual Function Mechanism of Alkane Aromatization over H-HZSM-5 Supported Ga, Zn, Pt Catalysts: Respective Role of Acidity and Additive Meriaudeau, Paul; Sapaly, Gilbert; Naccache, Claude Studies in Surface Science and Catalysis https://doi.org/10.1016/S0167-2991(08)61904-7	book	January 1991
Infrared photoluminescence characterization of long-wavelength HgCdTe detector materials Kurtz, S. R.; Bajaj, J.; Edwall, D. D. Semiconductor Science and Technology, Vol. 8, Issue 6S https://doi.org/10.1088/0268-1242/8/6S/015	journal	June 1993
Rationalizers and inventors in the drive for technical progress No authors listed Refractories, Vol. 10, Issue 7-8, p. 461-463 https://doi.org/10.1007/BF01291355	journal	July 1969
The ?multiple-sample concept? in materials research: Synthesis, compositional analysis and testing of entire multicomponent systems Hanak, J. J. Journal of Materials Science, Vol. 5, Issue 11 https://doi.org/10.1007/BF00558177	journal	November 1970
An efficient navigational aid for road travel Ram, Balasubramanian; Al-Awadhi, Waleed Computers & Industrial Engineering, Vol. 17, Issue 1-4 https://doi.org/10.1016/0360-8352(89)90124-1	journal	January 1989
In vitro selection of RNA molecules that bind specific ligands Ellington, Andrew D.; Szostak, Jack W. Nature, Vol. 346, Issue 6287 https://doi.org/10.1038/346818a0	journal	August 1990
15 Preparation of Two-dimensional Arrays of Soluble Proteins as Demonstrated for Bacterial D-Ribulose-1,5-bisphosphate Carboxylase/Oxygenase Holzenburg, Andreas Methods in Microbiology https://doi.org/10.1016/S0580-9517(08)70059-X	book	January 1988
Micro vials on a silicon wafer for sample introduction in capillary electrophoresis Jansson, Mårten; Emmer, Åssa; Roeraade, Johan Journal of Chromatography A, Vol. 626, Issue 2 https://doi.org/10.1016/0021-9673(92)85427-U	journal	December 1992
A multifunctional in situ catalyst characterization apparatus Serrano, Carlos; Carberry, J. J. Applied Catalysis, Vol. 19, Issue 1 https://doi.org/10.1016/S0166-9834(00)82675-5	journal	January 1985
La-Eu Cuprates as Catalysts for Phenol Oxidation Forni, L.; Oliva, C.; Vishniakov, A. V. Journal of Catalysis, Vol. 145, Issue 1 https://doi.org/10.1006/jcat.1994.1023	journal	January 1994
Random peptide libraries: a source of specific protein binding molecules Devlin, J.; Panganiban, L.; Devlin, P. Science, Vol. 249, Issue 4967 https://doi.org/10.1126/science.2143033	journal	July 1990
Catalytic antibodies Tramontano, A.; Janda, K.; Lerner, R. Science, Vol. 234, Issue 4783 https://doi.org/10.1126/science.3787261	journal	December 1986
The Current Status of Heterocyclic Combinatorial Libraries Nefzi, Adel; Ostresh, John M.; Houghten, Richard A. Chemical Reviews, Vol. 97, Issue 2 https://doi.org/10.1021/cr960010b	journal	April 1997
In-situ Fourier transform infrared studies of reaction mechanisms in heterogeneous catalysis Lavalley, Jean-Claude; Maache, Mohamed; Saussey, Jacques San Dieg - DL Tentative, SPIE Proceedings https://doi.org/10.1117/12.23098	conference	November 1990
Standing temperature waves on electrically heated catalytic ribbons Lobban, Lance; Philippou, Georgios; Luss, Dan The Journal of Physical Chemistry, Vol. 93, Issue 2 https://doi.org/10.1021/j100339a045	journal	January 1989
固定化金属錯体の有機合成への応用 Toshima, Naoki Journal of Synthetic Organic Chemistry, Japan, Vol. 36, Issue 11 https://doi.org/10.5059/yukigoseikyokaishi.36.909	journal	January 1978
Infrared Study of CO Oxidation over Pt-Rh/Al2O3 Catalysts Anderson, J. A. Journal of Catalysis, Vol. 142, Issue 1 https://doi.org/10.1006/jcat.1993.1197	journal	July 1993
Surface Analysis with FT-IR Emission Spectroscopy Sullivan, David H.; Conner, W. Curtis; Harold, Michael P. Applied Spectroscopy, Vol. 46, Issue 5 https://doi.org/10.1366/0003702924124844	journal	May 1992
Four-reactor apparatus for chromatographic studies of catalysts and sorbents Steininger, Mieczyslaw; Liszka, Marian; Rutkowski, Marian Journal of Chromatography A, Vol. 243, Issue 2 https://doi.org/10.1016/S0021-9673(00)82418-8	journal	July 1982
IR Emission Analysis of Temperature Profiles in Pt/SiO2 Catalysts during Exothermic Reactions Georgiades, George; Self, Valerie A.; Sermon, Paul A. Angewandte Chemie International Edition in English, Vol. 26, Issue 10 https://doi.org/10.1002/anie.198710421	journal	October 1987
The effect of grain size on the superconducting transition temperature of the transition metals Hanak, J. J.; Gittleman, J. I.; Pellicane, J. P. Physics Letters A, Vol. 30, Issue 3 https://doi.org/10.1016/0375-9601(69)90936-0	journal	October 1969
Spectroscopic investigations on deactivation of zeolite catalysts during reactions of olefins Karge, H. G.; Boldingh, E. Catalysis Today, Vol. 3, Issue 5 https://doi.org/10.1016/0920-5861(88)87018-4	journal	September 1988
Influence of the Synthesis Procedure and Chemical Composition on the Activity of Titanium in Ti-Beta Catalysts Camblor, M. A.; Corma, A.; Martinez, A. New Developments in Selective Oxidation II, Proceedings of the Second World Congress and Fourth European Workshop Meeting https://doi.org/10.1016/S0167-2991(08)63446-1	book	January 1994
The effect of solvent on the styrene-acrylonitrile copolymerization Hill, D. J. T.; Lang, A. P.; Munro, P. D. European Polymer Journal, Vol. 28, Issue 4 https://doi.org/10.1016/0014-3057(92)90260-9	journal	April 1992
Acid-base properties of silica-aluminas: use of 1-butanol dehydration as a test reaction Berteau, P.; Delmon, B.; Dallons, J. -L. Applied Catalysis, Vol. 70, Issue 1 https://doi.org/10.1016/S0166-9834(00)84173-1	journal	January 1991
Purification and crystallization of components of the protein-synthesizing system from Thermus thermophilus Garber, M. B.; Agalarov, S. Ch.; Eliseikina, I. A. Journal of Crystal Growth, Vol. 110, Issue 1-2 https://doi.org/10.1016/0022-0248(91)90890-H	journal	March 1991
The design and construction of a multichannel microreactor for catalyst evaluation Creer, J. Graham; Jackson, Peter; Pandy, Gordon Applied Catalysis, Vol. 22, Issue 1 https://doi.org/10.1016/S0166-9834(00)82596-8	journal	January 1986
Infrared Thermographic Screening of Combinatorial Libraries of Heterogeneous Catalysts Moates, F. C.; Somani, M.; Annamalai, J. Industrial & Engineering Chemistry Research, Vol. 35, Issue 12 https://doi.org/10.1021/ie960476k	journal	January 1996

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