Methods for production of proteins in host cells

Donnelly, Mark; Joachimiak, Andrzej

Title: Methods for production of proteins in host cells

Patent · Tue Jan 13 00:00:00 EST 2004

OSTI ID:1174681

Donnelly, Mark; Joachimiak, Andrzej

The present invention provides methods for the production of proteins, particularly toxic proteins, in host cells. The invention provides methods which use a fusion protein comprising a chaperonin binding domain in host cells induced or regulated to have increased levels of chaperonin which binds the chaperonin binding domain.

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Research Organization:: Genecor International, Inc., Rochester, NY (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: W-31-198-ENG-38

Assignee:: Genecor International, Inc. (Rochester, NY)

Patent Number(s):: 6,677,139

Application Number:: 09/470,830

OSTI ID:: 1174681

Country of Publication:: United States

Language:: English

References (29)

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