skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: High Sensitivity SPECT for Small Animals and Plants

Abstract

Imaging systems using single gamma-ray emitting radioisotopes typically implement collimators in order to form the images. However, a tradeoff in sensitivity is inherent in the use of collimators, and modern preclinical single-photon emission computed tomography (SPECT) systems detect a very small fraction of emitted gamma-rays (<0.3%). We have built a collimator-less system, which can reach sensitivity of 40% for 99mTc imaging, while still producing images of sufficient spatial resolution for certain applications in thin objects such as mice, small plants, and well plates used for in vitro experiments.

Authors:
 [1]
  1. UC Davis
Publication Date:
Research Org.:
UC Davis
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
OSTI Identifier:
1171466
Report Number(s):
DOE-UCDAVIS-05311
DOE Contract Number:
SC0005311
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
SPECT; nuclear imaging; plant imaging

Citation Formats

Mitchell, Gregory S. High Sensitivity SPECT for Small Animals and Plants. United States: N. p., 2015. Web. doi:10.2172/1171466.
Mitchell, Gregory S. High Sensitivity SPECT for Small Animals and Plants. United States. doi:10.2172/1171466.
Mitchell, Gregory S. Sat . "High Sensitivity SPECT for Small Animals and Plants". United States. doi:10.2172/1171466. https://www.osti.gov/servlets/purl/1171466.
@article{osti_1171466,
title = {High Sensitivity SPECT for Small Animals and Plants},
author = {Mitchell, Gregory S.},
abstractNote = {Imaging systems using single gamma-ray emitting radioisotopes typically implement collimators in order to form the images. However, a tradeoff in sensitivity is inherent in the use of collimators, and modern preclinical single-photon emission computed tomography (SPECT) systems detect a very small fraction of emitted gamma-rays (<0.3%). We have built a collimator-less system, which can reach sensitivity of 40% for 99mTc imaging, while still producing images of sufficient spatial resolution for certain applications in thin objects such as mice, small plants, and well plates used for in vitro experiments.},
doi = {10.2172/1171466},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sat Feb 28 00:00:00 EST 2015},
month = {Sat Feb 28 00:00:00 EST 2015}
}

Technical Report:

Save / Share: