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System and method for compressive scanning electron microscopy

Patent ·
OSTI ID:1167207

A scanning transmission electron microscopy (STEM) system is disclosed. The system may make use of an electron beam scanning system configured to generate a plurality of electron beam scans over substantially an entire sample, with each scan varying in electron-illumination intensity over a course of the scan. A signal acquisition system may be used for obtaining at least one of an image, a diffraction pattern, or a spectrum from the scans, the image, diffraction pattern, or spectrum representing only information from at least one of a select subplurality or linear combination of all pixel locations comprising the image. A dataset may be produced from the information. A subsystem may be used for mathematically analyzing the dataset to predict actual information that would have been produced by each pixel location of the image.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
awrence Livermore National Security, LLC (Livermore, CA)
Patent Number(s):
8,933,401
Application Number:
14/063,319
OSTI ID:
1167207
Country of Publication:
United States
Language:
English

References (31)

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X-Ray Spectrum Processing and Multivariate Analysis book January 1998
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EDX spectrum modelling and multivariate analysis of sub-nanometer segregation journal April 1999
Dose-limited spectroscopic imaging of soft materials by low-loss EELS in the scanning transmission electron microscope journal August 2008
Boron segregation to austenite grain boundary in low alloy steel measured by aberration corrected STEM–EELS journal October 2012
Mapping chemical and bonding information using multivariate analysis of electron energy-loss spectrum images journal October 2006
Observation of three-dimensional elemental distributions of a Si device using a 360°-tilt FIB and the cold field-emission STEM system journal November 2008
Multivariate statistics applications in phase analysis of STEM-EDS spectrum images journal January 2010
Extracting physically interpretable data from electron energy-loss spectra journal October 2010
Point defect characterization in HAADF-STEM images using multivariate statistical analysis journal February 2011
Analysis of EEL spectrum of low-loss region using the Cs-corrected STEM–EELS method and multivariate analysis journal April 2011
EEL spectroscopic tomography: Towards a new dimension in nanomaterials analysis journal November 2012
Key Parameters Affecting Quantitative Analysis of STEM-EDS Spectrum Images journal April 2010
Data Processing for Atomic Resolution Electron Energy Loss Spectroscopy journal June 2012
Two-Dimensional Correlation Localized Surface Plasmon Resonance Spectroscopy for Analysis of the Interaction between Metal Nanoparticles and Bovine Serum Albumin journal November 2010
3D Nanoscale Characterization of Thin-Film Organic Photovoltaic Device Structures via Spectroscopic Contrast in the TEM 1 journal September 2010
Chemometric and Microscopic Analyses for the Size Growth of Monolayer-Protected Gold Nanoparticles during Their Superlattice Formation journal December 2007
Physical vs Photolithographic Patterning of Plasma Polymers: An Investigation by ToF−SSIMS and Multivariate Analysis journal March 2010
Preparation of a leaf-like CdS micro-/nanostructure and its enhanced gas-sensing properties for detecting volatile organic compounds journal January 2012
Multivariate statistical methods for the analysis of microscope image series: applications in materials science journal April 1998
Review of recent advances in spectrum imaging and its extension to reciprocal space journal April 2009
The potential for Bayesian compressive sensing to significantly reduce electron dose in high-resolution STEM images journal October 2013
Single-pixel imaging via compressive sampling journal March 2008
Robust uncertainty principles: exact signal reconstruction from highly incomplete frequency information journal February 2006
Near-Optimal Signal Recovery From Random Projections: Universal Encoding Strategies? journal January 2006
Effects of Ampholyte Dissociation Constants on Protein Separation in On-Chip Isoelectric Focusing journal July 2008
Polymorph Transformation in Paracetamol Monitored by In-line NIR Spectroscopy During a Cooling Crystallization Process journal June 2011
Depth-Resolved EELS and Chemical State Mapping of N+-Implanted TiO2 Photocatalyst journal January 2007

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