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Title: Advanced Mass Spectrometry Methods.


Abstract not provided.

Publication Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
Report Number(s):
DOE Contract Number:
Resource Type:
Resource Relation:
Conference: Proposed for presentation at the GNEP Safeguards Working Group Meeting held April 12-13, 2007 in Salt Lake City, UT.
Country of Publication:
United States

Citation Formats

Cipiti, Benjamin B. Advanced Mass Spectrometry Methods.. United States: N. p., 2007. Web.
Cipiti, Benjamin B. Advanced Mass Spectrometry Methods.. United States.
Cipiti, Benjamin B. Sun . "Advanced Mass Spectrometry Methods.". United States. doi:.
title = {Advanced Mass Spectrometry Methods.},
author = {Cipiti, Benjamin B.},
abstractNote = {Abstract not provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Apr 01 00:00:00 EDT 2007},
month = {Sun Apr 01 00:00:00 EDT 2007}

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  • Although the ability to count alpha particles by liquid scintillation methods has been long recognized, limited use has been made of the method because of problems of high background and alpha energy identification. In recent years some new developments in methods of introducing the alpha-emitting nuclide to the scintillator, in detector construction, and in electronics for processing the energy analog and time analog signals from the detector have allowed significant alleviation of the problems of alpha spectrometry by liquid scintillation. Energy resolutions of 200 to 300 keV full peak width at half maximum and background counts of < 0.01 counts/minmore » with rejection with rejection of > 99% of all beta plus gamma interference is now possible. Alpha liquid scintillation spectrometry is now suitable for a wide range of applications, from the accurate quantitative determination of relatively large amounts of known nuclides in laboratory-generated samples to the detection and identification of very small, subpicocurie amounts of alpha emitters in environmental-type samples. Suitable nuclide separation procedures, sample preparation methods, and instrument configurations are available for a variety of analyses.« less
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  • Novel sampling approaches have been investigated to improve the analytical utility of thermal desorption Direct Sampling Ion Trap Mass Spectrometry (DSITMS). Because DSITMS involves the direct introduction of samples into an ion trap mass spectrometer, problems with detection capabilities (sensitivity and selectivity) can often occur when performing trace analysis in complex matrices. Various sampling approaches have been evaluated to improve thermal desorption detection capabilities and to extend the utilities of DSITMS methodologies without significantly increasing analysis times or the cost-effectiveness of DSITMS methods. Three sampling approaches have been investigated including solid phase microextraction (SPME), solid phase extraction columns (SPEC), andmore » purge and trap.« less
  • One emphasis in aerosol research includes the development of methods capable of single particle analysis in real time. Single particle measurements cover a broad range of both physical and chemical properties, such as size, shape, temperature and elemental or chemical composition. Various instruments have been developed which focus on the measurement of one or more of these properties. Particle size influences particle transportation and reactivity, while chemical composition determines which reactions may take place on the particle surface. Therefore, various researchers have placed an emphasis on determining the size and composition of individual aerosol particles. The two most common particlemore » sizing methods coupled with mass spectrometry are light scattering intensity measurements and aerodynamics particle sizing.« less
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