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Methods for making nucleotide probes for sequencing and synthesis

Patent ·
OSTI ID:1140127
Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided.
Research Organization:
Harvard College, Cambridge, MA (USA).
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-02ER63445;
Assignee:
President and Fellows of Harvard College (Cambridge, MA)
Patent Number(s):
8,771,950
Application Number:
12/187,460
OSTI ID:
1140127
Country of Publication:
United States
Language:
English

References (14)

Mutation detection by solid phase primer extension journal January 1996
Universal DNA microarray method for multiplex detection of low abundance point mutations journal September 1999
The mechanisms of DNA topoisomerases journal April 1995
Mutation detection and single-molecule counting using isothermal rolling-circleamplification journal July 1998
Accurate multiplex gene synthesis from programmable DNA microchips journal December 2004
Sequencing genomes from single cells by polymerase cloning journal May 2006
Multiplexed genotyping with sequence-tagged molecular inversion probes journal May 2003
Toward genome-wide SNP genotyping journal June 2005
Circle-to-circle amplification for precise and sensitive DNA analysis journal March 2004
Cell-free cloning using φ29 DNA polymerase journal November 2005
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery journal October 2005
Parallel gene analysis with allele-specific padlock probes and tag microarrays journal September 2003
Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay journal January 2005
Allelic Variation in Human Gene Expression journal August 2002

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