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Title: Sheathless interface for coupling capillary electrophoresis with mass spectrometry

Abstract

A sheathless interface for coupling capillary electrophoresis (CE) with mass spectrometry is disclosed. The sheathless interface includes a separation capillary for performing CE separation and an emitter capillary for electrospray ionization. A portion of the emitter capillary is porous or, alternatively, is coated to form an electrically conductive surface. A section of the emitter capillary is disposed within the separation capillary, forming a joint. A metal tube, containing a conductive liquid, encloses the joint.

Inventors:
; ;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1134337
Patent Number(s):
8,754,370
Application Number:
13/788,854
Assignee:
Battelle Memorial Institute (Richland, WA)
DOE Contract Number:  
AC05-76RLO1830
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 Mar 07
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION

Citation Formats

Wang, Chenchen, Tang, Keqi, and Smith, Richard D. Sheathless interface for coupling capillary electrophoresis with mass spectrometry. United States: N. p., 2014. Web.
Wang, Chenchen, Tang, Keqi, & Smith, Richard D. Sheathless interface for coupling capillary electrophoresis with mass spectrometry. United States.
Wang, Chenchen, Tang, Keqi, and Smith, Richard D. 2014. "Sheathless interface for coupling capillary electrophoresis with mass spectrometry". United States. https://www.osti.gov/servlets/purl/1134337.
@article{osti_1134337,
title = {Sheathless interface for coupling capillary electrophoresis with mass spectrometry},
author = {Wang, Chenchen and Tang, Keqi and Smith, Richard D.},
abstractNote = {A sheathless interface for coupling capillary electrophoresis (CE) with mass spectrometry is disclosed. The sheathless interface includes a separation capillary for performing CE separation and an emitter capillary for electrospray ionization. A portion of the emitter capillary is porous or, alternatively, is coated to form an electrically conductive surface. A section of the emitter capillary is disposed within the separation capillary, forming a joint. A metal tube, containing a conductive liquid, encloses the joint.},
doi = {},
url = {https://www.osti.gov/biblio/1134337}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {6}
}

Works referenced in this record:

Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry
journal, September 2000


Capillary Electrophoresis to Mass Spectrometry Interface Using a Porous Junction
journal, May 2003


Capillary electrophoresis–electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments
journal, December 2012


Isotachophoresis as an on-line concentration pretreatment technique in capillary electrophoresis
journal, January 1991


Ultrasensitive Sample Quantitation via Selected Reaction Monitoring Using CITP/CZE–ESI-Triple Quadrupole MS
journal, November 2012