Dielectrokinetic chromatography and devices thereof
Abstract
Disclosed herein are methods and devices for dielectrokinetic chromatography. As disclosed, the devices comprise microchannels having at least one perturber which produces a non-uniformity in a field spanning the width of the microchannel. The interaction of the field non-uniformity with a perturber produces a secondary flow which competes with a primary flow. By decreasing the size of the perturber the secondary flow becomes significant for particles/analytes in the nanometer-size range. Depending on the nature of a particle/analyte present in the fluid and its interaction with the primary flow and the secondary flow, the analyte may be retained or redirected. The composition of the primary flow can be varied to affect the magnitude of primary and/or secondary flows on the particles/analytes and thereby separate and concentrate it from other particles/analytes.
- Inventors:
- Publication Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1129393
- Patent Number(s):
- 8,702,946
- Application Number:
- 12/128,913
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2008 May 29
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Chirica, Gabriela S, Fiechtner, Gregory J, and Singh, Anup K. Dielectrokinetic chromatography and devices thereof. United States: N. p., 2014.
Web.
Chirica, Gabriela S, Fiechtner, Gregory J, & Singh, Anup K. Dielectrokinetic chromatography and devices thereof. United States.
Chirica, Gabriela S, Fiechtner, Gregory J, and Singh, Anup K. 2014.
"Dielectrokinetic chromatography and devices thereof". United States. https://www.osti.gov/servlets/purl/1129393.
@article{osti_1129393,
title = {Dielectrokinetic chromatography and devices thereof},
author = {Chirica, Gabriela S and Fiechtner, Gregory J and Singh, Anup K},
abstractNote = {Disclosed herein are methods and devices for dielectrokinetic chromatography. As disclosed, the devices comprise microchannels having at least one perturber which produces a non-uniformity in a field spanning the width of the microchannel. The interaction of the field non-uniformity with a perturber produces a secondary flow which competes with a primary flow. By decreasing the size of the perturber the secondary flow becomes significant for particles/analytes in the nanometer-size range. Depending on the nature of a particle/analyte present in the fluid and its interaction with the primary flow and the secondary flow, the analyte may be retained or redirected. The composition of the primary flow can be varied to affect the magnitude of primary and/or secondary flows on the particles/analytes and thereby separate and concentrate it from other particles/analytes.},
doi = {},
url = {https://www.osti.gov/biblio/1129393},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 22 00:00:00 EDT 2014},
month = {Tue Apr 22 00:00:00 EDT 2014}
}
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Works referencing / citing this record:
Dielectrokinetic chromatography devices
patent, December 2014
- Chirica, Gabriela S.; Fiechtner, Gregory J.; Singh, Anup K.
- US Patent Document 8,911,606