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Title: Functionalized magnetic nanoparticle analyte sensor

Patent ·
OSTI ID:1128682
; ; ; ; ; ;

A method and system for simply and efficiently determining quantities of a preselected material in a particular solution by the placement of at least one superparamagnetic nanoparticle having a specified functionalized organic material connected thereto into a particular sample solution, wherein preselected analytes attach to the functionalized organic groups, these superparamagnetic nanoparticles are then collected at a collection site and analyzed for the presence of a particular analyte.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RLO1830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
8,679,458
Application Number:
11/936,405
OSTI ID:
1128682
Resource Relation:
Patent File Date: 2007 Nov 07
Country of Publication:
United States
Language:
English

References (11)

Method of separating cationic from anionic beads in mixed resin beds patent June 1985
Calcium ion selective electrode patent April 1992
Fe/Au nanoparticles and methods patent March 2007
Non-alloying core shell nanoparticles patent-application November 2002
Non-alloying core shell nanoparticles patent-application July 2003
Magnetic nanomaterials and methods for detection of biological materials patent-application May 2004
Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules patent-application May 2005
Microparticle-based diagnostic methods patent-application June 2005
Determination of calcium in complex samples using functional magnetic beads combined with electrodeless/sheathless electrospray ionization mass spectrometry journal January 2006
Low-Field Magnetic Separation of Monodisperse Fe3O4 Nanocrystals journal November 2006
Removal of Heavy Metals from Aqueous Systems with Thiol Functionalized Superparamagnetic Nanoparticles journal July 2007

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