Variant Humicola grisea CBH1.1

Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

Title: Variant Humicola grisea CBH1.1

Patent · Tue Mar 18 00:00:00 EDT 2014

OSTI ID:1127153

Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

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Research Organization:: National Renewable Energy Laboratory (NREL), Golden, CO (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC36-99GO10337

Assignee:: Danisco US Inc. (Palo Alto, CA)

Patent Number(s):: 8,673,611

Application Number:: 13/542,482

OSTI ID:: 1127153

Country of Publication:: United States

Language:: English

References (70)

Detergent composition for clothing incorporating a cellulase Suzuki, Akira; Ito, Susumu; Okamoto, Kikuhiko https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4822516 US Patent Document 4,822,516	patent	April 1989
Method for treating cotton-containing fabric with a cellulase composition containing endoglucanase components and which composition is free of exo-cellobiohydrolase I Clarkson, Kathleen A.; Larenas, Edward; Weiss, Geoffrey L. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5246853 US Patent Document 5,246,853	patent	September 1993
Enzyme capable of degrading cellullose or hemicellulose Woldike, Helle Fabricius; Hagen, Fred; Hjort, Carsten https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5457046 US Patent Document 5,457,046	patent	October 1995
DNA sequence encoding endoglucanase III cellulase Ward, Michael; Clarkson, Kathleen A.; Larenas, Edmund https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5475101 US Patent Document 5,475,101	patent	December 1995
Exploitation of the cellulase enzyme complex of neurospora Radford, Alan; Parish, John Howard https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5955270 US Patent Document 5,955,270	patent	September 1999
Variant EGIII-like cellulase compositions Mitchinson, Colin; Wendt, Dan J. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6268328 US Patent Document 6,268,328	patent	July 2001
CBH1 homologs and variant CBH1 cellulases Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7452707 US Patent Document 7,452,707	patent	November 2008
Novel variant hypocrea jecorina CBH1cellulases Day, Anthony; Goedegebuur, Frits; Gualfetti, Peter https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20050277172 US Patent Application 10/641678; 20050277172	patent-application	December 2005
The plasmid replicator AMA1 in Aspergillus nidulans is an inverted duplication of a low-copy-number dispersed genomic repeat Aleksenko, Alexei; Clutterbuck, A. John Molecular Microbiology, Vol. 19, Issue 3, p. 565-574 https://doi.org/10.1046/j.1365-2958.1996.400937.x	journal	February 1996
Basic local alignment search tool Altschul, Stephen F.; Gish, Warren; Miller, Webb Journal of Molecular Biology, Vol. 215, Issue 3, p. 403-410 https://doi.org/10.1016/S0022-2836(05)80360-2	journal	October 1990
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs Altschul, Stephen F.; Madden, Thomas L.; Schäffer, Alejandro A. Nucleic Acids Research, Vol. 25, Issue 17, p. 3389-3402 https://doi.org/10.1093/nar/25.17.3389	journal	September 1997
ACEII, a Novel Transcriptional Activator Involved in Regulation of Cellulase and Xylanase Genes of Trichoderma reesei Aro, Nina; Saloheimo, Anu; Ilmén, Marja Journal of Biological Chemistry, Vol. 276, Issue 26, p. 24309-24314 https://doi.org/10.1074/jbc.M003624200	journal	April 2001
Hydrolysis of Cellulose Using Ternary Mixtures of Purified Cellulases Baker, John O.; Ehrman, Christine I.; Adney, William S. Biotechnology for Fuels and Chemicals https://doi.org/10.1007/978-1-4612-1814-2_37	book	January 1998
Efficient transformation of Dictyostelium discoideum amoebae. Barclay, S. L.; Meller, E. Molecular and Cellular Biology, Vol. 3, Issue 12, p. 2117-2130 https://doi.org/10.1128/MCB.3.12.2117	journal	December 1983
Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei Cel7A and its E223S/ A224H/L225V/T226A/D262G mutant Becker, Dieter; Braet, Christophe; Brumer, Harry Biochemical Journal, Vol. 356, Issue 1, p. 19-30 https://doi.org/10.1042/bj3560019	journal	May 2001
Isolation of uridine auxotrophs from Trichoderma reesei and efficient transformation with the cloned ura3 and ura5 genes Bergès, Thierry; Barreau, Christian Current Genetics, Vol. 19, Issue 5, p. 359-365 https://doi.org/10.1007/BF00309596	journal	May 1991
Improved transformation efficiency of Aspergillus niger using the homologous niaD gene for nitrate reductase Campbell, Edward I.; Unkles, Shiela E.; Macro, Janet A. Current Genetics, Vol. 16, Issue 1, p. 53-56 https://doi.org/10.1007/BF00411084	journal	July 1989
Chapter 43 Rethinking Your Purification Procedure Deutscher, Murray P. Guide to Protein Purification, 2nd Edition https://doi.org/10.1016/S0076-6879(09)63043-3	book	January 2009
Analytical separation of Trichoderma reesei cellulases by ion-exchange fast protein liquid chromatography Ellouz, S.; Durand, H.; Tiraby, G. Journal of Chromatography A, Vol. 396, p. 307-317 https://doi.org/10.1016/S0021-9673(01)94068-3	journal	January 1987
Purification and characterization of a β-glucosidase from solid-state cultures of Humicola grisea var. thermoidea Filho, Edivaldo Ximenes Ferreira Canadian Journal of Microbiology, Vol. 42, Issue 1, p. 1-5 https://doi.org/10.1139/m96-001	journal	January 1996
Characterization of cellulases by HPLC separation Fliess, A.; Schügerl, K. European Journal of Applied Microbiology and Biotechnology, Vol. 17, Issue 5, p. 314-318 https://doi.org/10.1007/BF00508028	journal	January 1983
Urea and Thermal Equilibrium Denaturation Studies on the Dimerization Domain of Escherichia coli Trp Repressor Gloss, Lisa M.; Matthews, C. Robert Biochemistry, Vol. 36, Issue 19, p. 5612-5623 https://doi.org/10.1021/bi970056e	journal	May 1997
Cloning and relational analysis of 15 novel fungal endoglucanases from family 12 glycosyl hydrolase Goedegebuur, Frits; Fowler, Timothy; Phillips, Jay Current Genetics, Vol. 41, Issue 2, p. 89-98 https://doi.org/10.1007/s00294-002-0290-2	journal	May 2002
Characteristics of fungal cellulases Goyal, Anil; Ghosh, Bijan; Eveleigh, Douglas Bioresource Technology, Vol. 36, Issue 1, p. 37-50 https://doi.org/10.1016/0960-8524(91)90098-5	journal	January 1991
Cloning, sequencing and overexpression of a Rhodothermus marinus gene encoding a thermostable cellulase of glycosyl hydrolase family 12 Halldórsdóttir, S.; Thórólfsdót, E. T.; Spilliaert, R. Applied Microbiology and Biotechnology, Vol. 49, Issue 3, p. 277-284 https://doi.org/10.1007/s002530051169	journal	March 1998
Rapid transformation of high cellulase-producing mutant strains of Trichoderma reesei by microprojectile bombardment Hazell, B.W.; Te'O, V.S.J.; Bradner, J.R. Letters in Applied Microbiology, Vol. 30, Issue 4, p. 282-286 https://doi.org/10.1046/j.1472-765x.2000.00715.x	journal	April 2000
Purification and properties of an extracellular β-glucosidase from Lenzites trabea Herr, D.; Baumer, F.; Dellweg, H. European Journal of Applied Microbiology and Biotechnology, Vol. 5, Issue 1, p. 29-36 https://doi.org/10.1007/BF00515684	journal	January 1978
Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides. Hu, Q. J.; Bautista, C.; Edwards, G. M. Molecular and Cellular Biology, Vol. 11, Issue 11, p. 5792-5799 https://doi.org/10.1128/MCB.11.11.5792	journal	November 1991
Isolation of genomic clones containing the amdS gene of Aspergillus nidulans and their use in the analysis of structural and regulatory mutations. Hynes, M. J.; Corrick, C. M.; King, J. A. Molecular and Cellular Biology, Vol. 3, Issue 8, p. 1430-1439 https://doi.org/10.1128/MCB.3.8.1430	journal	August 1983
9 Heterologous Protein Production by Filamentous Fungi Jeenes, David J.; Mackenzie, Donald A.; Roberts, Ian N. Biotechnology and Genetic Engineering Reviews, Vol. 9, Issue 1, p. 327-367 https://doi.org/10.1080/02648725.1991.10750006	journal	December 1991
Cloning and sequencing of the cDNA encoding β-glucosidase 1 from Aspergillus aculeatus Kawaguchi, Takashi; Enoki, Tatsuji; Tsurumaki, Shinji Gene, Vol. 173, Issue 2, p. 287-288 https://doi.org/10.1016/0378-1119(96)00179-5	journal	September 1996
Cellulase families and their genes Knowles, Jonathan; Lehtovaara, Päivi; Teeri, Tuula Trends in Biotechnology, Vol. 5, Issue 9, p. 255-261 https://doi.org/10.1016/0167-7799(87)90102-8	journal	September 1987
Biophysical electron microscopy Hawkes, P. W.; Valdre, V. Trends in Biochemical Sciences, Vol. 16, p. 483 https://doi.org/10.1016/0968-0004(91)90188-2	journal	January 1991
Simultaneous saccharification and fermentation of lignocellulosic wastes to ethanol using a thermotolerant yeast Hari Krishna, S.; Janardhan Reddy, T.; Chowdary, G. V. Bioresource Technology, Vol. 77, Issue 2, p. 193-196 https://doi.org/10.1016/S0960-8524(00)00151-6	journal	April 2001
The roles and function of cellulose-binding domains Linder, Markus; Teeri, Tuula T. Journal of Biotechnology, Vol. 57, Issue 1-3, p. 15-28 https://doi.org/10.1016/S0168-1656(97)00087-4	journal	September 1997
Cloning and characterization of the ethanol utilization regulon in Aspergillus nidulans Lockington, Robin A.; Scaly-Lewis, H. M.; Scazzocchio, C. Gene, Vol. 33, Issue 2, p. 137-149 https://doi.org/10.1016/0378-1119(85)90088-5	journal	January 1985
Nucleotide sequence of the triosephosphate isomerase gene from Aspergillus nidulans: Implications for a differential loss of introns McKnight, Gary L.; O'Hara, Patrick J.; Parker, Michael L. Cell, Vol. 46, Issue 1, p. 143-147 https://doi.org/10.1016/0092-8674(86)90868-8	journal	July 1986
Ion-exchange chromatographic purification and quantitative analysis of Trichoderma reesei cellulases cellobiohydrolase I, II and endoglucanase II by fast protein liquid chromatography Medve, József; Lee, Dora; Tjerneld, Folke Journal of Chromatography A, Vol. 808, Issue 1-2, p. 153-165 https://doi.org/10.1016/S0021-9673(98)00132-0	journal	May 1998
Site-directed mutagenesis of the putative catalytic residues of Trichoderma reesci cellobiohydrolase I and endoglucanase I Mitsuishi, Yasushi; Nitisinprasert, Sunee; Saloheimo, Markku FEBS Letters, Vol. 275, Issue 1-2, p. 135-138 https://doi.org/10.1016/0014-5793(90)81457-Y	journal	November 1990
Isolation and Characterization of Acidothermus cellulolyticus gen. nov., sp. nov., a New Genus of Thermophilic, Acidophilic, Cellulolytic Bacteria MOHAGHEGHI, A.; GROHMANN, K.; HIMMEL, M. International Journal of Systematic Bacteriology, Vol. 36, Issue 3, p. 435-443 https://doi.org/10.1099/00207713-36-3-435	journal	July 1986
Specific quantification of trichoderma reesei cellulases in reconstituted mixtures and its application to cellulase-cellulose binding studies Nidetzky, Bernd; Claeyssens, Marc Biotechnology and Bioengineering, Vol. 44, Issue 8, p. 961-966 https://doi.org/10.1002/bit.260440812	journal	October 1994
Molecular cloning and characterization of the glucoamylase gene of Aspergillus awamori. Nunberg, J. H.; Meade, J. H.; Cole, G. Molecular and Cellular Biology, Vol. 4, Issue 11, p. 2306-2315 https://doi.org/10.1128/MCB.4.11.2306	journal	November 1984
Homology between cellulase genes of Trichoderma reesei: complete nucleotide sequence of the endoglucanase I gene Penttilä, Merja; Lehtovaara, Päivi; Nevalainen, Helena Gene, Vol. 45, Issue 3, p. 253-263 https://doi.org/10.1016/0378-1119(86)90023-5	journal	January 1986
A versatile transformation system for the cellulolytic filamentous fungus Trichoderma reesei Penttilä, Merja; Nevalainen, Helena; Rättö, Marjaana Gene, Vol. 61, Issue 2, p. 155-164 https://doi.org/10.1016/0378-1119(87)90110-7	journal	January 1987
Efficient secretion of two fungal cellobiohydrolases by Saccharomyces cerevisiae Penttilä, Merja E.; André, Lars; Lehtovaara, Päivi Gene, Vol. 63, Issue 1, p. 103-112 https://doi.org/10.1016/0378-1119(88)90549-5	journal	March 1988
CelS: a novel endoglucanase identified from Erwinia carotovora subsp. carotovora Saarilahti, Hannu T.; Henrissat, Bernard; Tapio Palva, E. Gene, Vol. 90, Issue 1, p. 9-14 https://doi.org/10.1016/0378-1119(90)90433-R	journal	May 1990
EGIII, a new endoglucanase from Trichoderma reesei: the characterization of both gene and enzyme Saloheimo, M.; Lehtovaara, P.; Penttilä, M. Gene, Vol. 63, Issue 1, p. 11-21 https://doi.org/10.1016/0378-1119(88)90541-0	journal	March 1988
A novel, small endoglucanase gene, egl5, from Trichoderma reesei isolated by expression in yeast Saloheimo, Anu; Henrissat, Bernard; Hoffrén, Anna-Marja Molecular Microbiology, Vol. 13, Issue 2, p. 219-228 https://doi.org/10.1111/j.1365-2958.1994.tb00417.x	journal	July 1994
cDNA Cloning of a Trichoderma reesei Cellulase and Demonstration of Endoglucanase Activity by Expression in Yeast Saloheimo, Markku; Nakari-SetaLa, Tiina; Tenkanen, Maija European Journal of Biochemistry, Vol. 249, Issue 2, p. 584-591 https://doi.org/10.1111/j.1432-1033.1997.00584.x	journal	October 1997
Dilute-Sulfuric Acid Pretreatment of Corn Stover in Pilot-Scale Reactor Schell, Daniel J.; Farmer, Jody; Newman, Millie Biotechnology for Fuels and Chemicals https://doi.org/10.1007/978-1-4612-0057-4_6	book	January 2003
Cellulases of Trichoderma reesei Schülein, Martin Methods in Enzymology, Vol. 160, p. 234-242 https://doi.org/10.1016/0076-6879(88)60125-X	journal	January 1988
[79] Purification of all glycolytic enzymes from one muscle extract Scopes, Robert K.; Stoter, Ann Methods in Enzymology, Vol. 90, p. 479-490 https://doi.org/10.1016/S0076-6879(82)90175-6	journal	January 1982
Characterization of the secreted cellulases of Trichoderma reesei wild type and mutants during controlled fermentations Sheir-Neiss, G.; Montenecourt, B. S. Applied Microbiology and Biotechnology, Vol. 20, Issue 1, p. 46-53 https://doi.org/10.1007/BF00254645	journal	July 1984
Enzymic activities of endo-1,4-β-d-glucanases purified from Trichoderma viride Shoemaker, S. P.; Brown, R. D. Biochimica et Biophysica Acta (BBA) - Enzymology, Vol. 523, Issue 1, p. 133-146 https://doi.org/10.1016/0005-2744(78)90016-5	journal	March 1978
Molecular Cloning of Exo–Cellobiohydrolase I Derived from Trichoderma Reesei Strain L27 Shoemaker, S.; Schweickart, V.; Ladner, M. Nature Biotechnology, Vol. 1, Issue 8, p. 691-696 https://doi.org/10.1038/nbt1083-691	journal	October 1983
Cloning and Sequencing of a Rhodothermus marinus Gene, bglA, Coding for a Thermostable beta-Glucanase and its Expression in Escherichia coli Spilliaert, Remi; Hreggvidsson, Gudmundur Oli; Kristjansson, Jakob Kristjan European Journal of Biochemistry, Vol. 224, Issue 3, p. 923-930 https://doi.org/10.1111/j.1432-1033.1994.00923.x	journal	September 1994
Trichoderma reesei cellobiohydrolase I with an endoglucanase cellulose-binding domain: action on bacterial microcrystalline cellulose Srisodsuk, Malee; Lehtiö, Janne; Linder, Markus Journal of Biotechnology, Vol. 57, Issue 1-3, p. 49-57 https://doi.org/10.1016/S0168-1656(97)00088-6	journal	September 1997
A New Model For Enzymatic Hydrolysis of Cellulose Based on the Two-Domain Structure of Cellobiohydrolase I Ståhlberg, Jerry; Johansson, Gunnar; Pettersson, Göran Nature Biotechnology, Vol. 9, Issue 3, p. 286-290 https://doi.org/10.1038/nbt0391-286	journal	March 1991
Trichoderma reesei cellulases and their core domains in the hydrolysis and modification of chemical pulp Suurnäkki, A.; Tenkanen, M.; Siika-aho, M. Cellulose, Vol. 7, Issue 2, p. 189-209 https://doi.org/10.1023/A:1009280109519	journal	June 2000
Homologous domains in Trichoderma reesei cellulolytic enzymes: Gene sequence and expression of cellobiohydrolase II Teeri, Tuula T.; Lehtovaara, Päivi; Kauppinen, Sakari Gene, Vol. 51, Issue 1, p. 43-52 https://doi.org/10.1016/0378-1119(87)90472-0	journal	January 1987
Studies on the chromatographic fractionation of Trichoderma reesei cellulases by hydrophobic interaction Tomaz, Cândida T.; Queiroz, João A. Journal of Chromatography A, Vol. 865, Issue 1-2, p. 123-128 https://doi.org/10.1016/S0021-9673(99)00851-1	journal	December 1999
Studies of the cellulolytic system of Trichoderma reesei QM 9414. Analysis of domain function in two cellobiohydrolases by limited proteolysis TOMME, Peter; TILBEURGH, Herman; PETTERSSON, Goran European Journal of Biochemistry, Vol. 170, Issue 3, p. 575-581 https://doi.org/10.1111/j.1432-1033.1988.tb13736.x	journal	January 1988
Codon optimization of xylanase gene xynB from the thermophilic bacterium Dictyoglomus thermophilum for expression in the filamentous fungus Trichoderma reesei Te'o, Valentino S.J.; Cziferszky, Angela E.; Bergquist, Peter L. FEMS Microbiology Letters, Vol. 190, Issue 1, p. 13-19 https://doi.org/10.1111/j.1574-6968.2000.tb09255.x	journal	September 2000
Separation of endo- and exo-type cellulases using a new affinity chromatography method van Tilbeurgh, Herman; Bhikhabhai, Ramagauri; Göran Pettersson, L. FEBS Letters, Vol. 169, Issue 2, p. 215-218 https://doi.org/10.1016/0014-5793(84)80321-X	journal	April 1984
Limited proteolysis of the cellobiohydrolase I from Trichoderma reesei: Separation of functional domains Van Tilbeurgh, Herman; Tomme, Peter; Claeyssens, Marc FEBS Letters, Vol. 204, Issue 2, p. 223-227 https://doi.org/10.1016/0014-5793(86)80816-X	journal	August 1986
Use of Aspergillus overproducing mutants, cured for intergrated plasmid, to overproduce heterologous proteins Ward, Michael; Wilson, Lori J.; Kodama, Katherine H. Applied Microbiology and Biotechnology, Vol. 39, Issue 6, p. 738-743 https://doi.org/10.1007/BF00164459	journal	August 1993
The cellulase of Fusarium solani . Purification and specificity of the β-(1→4)-glucanase and the β-d-glucosidase components Wood, T. M. Biochemical Journal, Vol. 121, Issue 3, p. 353-362 https://doi.org/10.1042/bj1210353	journal	February 1971
Methods for measuring cellulase activities Wood, Thomas M.; Bhat, K. Mahalingeshwara Methods in Enzymology, Vol. 160, p. 87-112 https://doi.org/10.1016/0076-6879(88)60109-1	journal	January 1988
Cloning, sequencing, and expression of the cellulase genes of Humicola grisea var. thermoidea Takashima, Shou; Nakamura, Akira; Hidaka, Makoto Journal of Biotechnology, Vol. 50, Issue 2-3, p. 137-147 https://doi.org/10.1016/0168-1656(96)01555-6	journal	October 1996
Isolation of the Gene and Characterization of the Enzymatic Properties of a Major Exoglucanase of Humicola grisea without a Cellulose-Binding Domain Takashima, S.; Iikura, H.; Nakamura, A. Journal of Biochemistry, Vol. 124, Issue 4 https://doi.org/10.1093/oxfordjournals.jbchem.a022172	journal	October 1998

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