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Title: Photobiological hydrogen production with switchable photosystem-II designer algae

Patent ·
OSTI ID:1124781

A process for enhanced photobiological H.sub.2 production using transgenic alga. The process includes inducing exogenous genes in a transgenic alga by manipulating selected environmental factors. In one embodiment inducing production of an exogenous gene uncouples H.sub.2 production from existing mechanisms that would downregulate H.sub.2 production in the absence of the exogenous gene. In other embodiments inducing an exogenous gene triggers a cascade of metabolic changes that increase H.sub.2 production. In some embodiments the transgenic alga are rendered non-regenerative by inducing exogenous transgenes for proton channel polypeptides that are targeted to specific algal membranes.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
ORNL
Patent Number(s):
8,653,331
Application Number:
12/648,567
OSTI ID:
1124781
Country of Publication:
United States
Language:
English

References (11)

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Coordinate Copper- and Oxygen-responsive Cyc6 and Cpx1 Expression in Chlamydomonas Is Mediated by the Same Element journal February 2000
Cloning of a streptomycin-production gene directing synthesis of N-methyl-l-glucosamine journal January 1986
Killing the messenger: short RNAs that silence gene expression journal June 2003
Temperature effect on production of hydrogen and oxygen byChlamydomonas cold strain CCMP1619 and wild-type 137c: Scientific note journal September 1995
Improvement of Photosynthetic CO2 Fixation at High Light Intensity Through Reduction of Chlorophyll Antenna Size book January 2002
Oxygen Tolerance of the H 2 -sensing [NiFe] Hydrogenase from Ralstonia eutropha H16 Is Based on Limited Access of Oxygen to the Active Site journal April 2005
Induced expression of melittin, an antimicrobial peptide, inhibits infection by Chlamydia trachomatis and Mycoplasma hominis in a HeLa cell line journal February 2002

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