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Title: System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source

Abstract

A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.

Inventors:
;
Publication Date:
Research Org.:
LANL (Los Alamos National Laboratory (LANL), Los Alamos, NM (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1107599
Patent Number(s):
8,564,776
Application Number:
12/903,003
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Graves, Steven W, and Habbersett, Robert C. System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source. United States: N. p., 2013. Web.
Graves, Steven W, & Habbersett, Robert C. System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source. United States.
Graves, Steven W, and Habbersett, Robert C. Tue . "System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source". United States. https://www.osti.gov/servlets/purl/1107599.
@article{osti_1107599,
title = {System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source},
author = {Graves, Steven W and Habbersett, Robert C},
abstractNote = {A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {10}
}

Patent:

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