Detection of magnetic resonance signals using a magnetoresistive sensor

Title: Detection of magnetic resonance signals using a magnetoresistive sensor

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Abstract

A method and apparatus are described wherein a micro sample of a fluidic material may be assayed without sample contamination using NMR techniques, in combination with magnetoresistive sensors. The fluidic material to be assayed is first subject to pre-polarization, in one embodiment, by passage through a magnetic field. The magnetization of the fluidic material is then subject to an encoding process, in one embodiment an rf-induced inversion by passage through an adiabatic fast-passage module. Thereafter, the changes in magnetization are detected by a pair of solid-state magnetoresistive sensors arranged in gradiometer mode. Miniaturization is afforded by the close spacing of the various modules.

Inventors:: Budker, Dmitry; Pines, Alexander; Xu, Shoujun; Hilty, Christian; Ledbetter, Micah P; Bouchard, Louis S

Publication Date:: 2013-10-01

Research Org.:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1107574

Patent Number(s):: 8,547,095

Application Number:: 12/753,306

Assignee:: The Regents of the University of California (Oakland, CA)

DOE Contract Number:: AC03-76SF00098; AC02-05CH11231

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION

Citation Formats


                    Budker, Dmitry, Pines, Alexander, Xu, Shoujun, Hilty, Christian, Ledbetter, Micah P, and Bouchard, Louis S. Detection of magnetic resonance signals using a magnetoresistive sensor.  United States: N. p., 2013. 
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                    Budker, Dmitry, Pines, Alexander, Xu, Shoujun, Hilty, Christian, Ledbetter, Micah P, & Bouchard, Louis S. Detection of magnetic resonance signals using a magnetoresistive sensor.  United States.

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                    Budker, Dmitry, Pines, Alexander, Xu, Shoujun, Hilty, Christian, Ledbetter, Micah P, and Bouchard, Louis S. Tue .  
        "Detection of magnetic resonance signals using a magnetoresistive sensor".  United States.  https://www.osti.gov/servlets/purl/1107574.

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@article{osti_1107574,

  title        = {Detection of magnetic resonance signals using a magnetoresistive sensor},

  author       = {Budker, Dmitry and Pines, Alexander and Xu, Shoujun and Hilty, Christian and Ledbetter, Micah P and Bouchard, Louis S},

  abstractNote = {A method and apparatus are described wherein a micro sample of a fluidic material may be assayed without sample contamination using NMR techniques, in combination with magnetoresistive sensors. The fluidic material to be assayed is first subject to pre-polarization, in one embodiment, by passage through a magnetic field. The magnetization of the fluidic material is then subject to an encoding process, in one embodiment an rf-induced inversion by passage through an adiabatic fast-passage module. Thereafter, the changes in magnetization are detected by a pair of solid-state magnetoresistive sensors arranged in gradiometer mode. Miniaturization is afforded by the close spacing of the various modules.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/1107574},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2013},

  month        = {10}

}

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