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Title: PhytoPET: Design and initial results of modular PET for plant biology

Abstract

We have developed a positron emission tomography (PET) system designed specifically for plant imaging in Phytotron at Duke University. Initial evaluation of a PhytoPET system to image the biodistribution of the positron emitting tracer {sup 11}C in live plants is presented. The mechanical arrangement of the detectors is designed to accommodate the unpredictable and random distribution in space of the plant parts such as stems, leaves, and roots. Prototyping such a system requires a completely new PET system design strategy different from preclinical and clinical applications. This PhytoPET design allows flexible arrangements of PET detectors based on individual standalone detector modules built from single 5 cm × 5 cm Hamamatsu H8500 position sensitive photomultiplier tubes. Each H8500 is coupled to a L YSO:Ce scintillator array composed of 48 × 48 elements that are 10 mm thick with a 1 mm pitch. Initial results provide planar PET images from two different arrangements (1 × 4 or 2 × 2) for flexible imaging capability.

Authors:
 [1];  [1];  [1];  [1];  [1];  [1]; ; ;
  1. JLAB
Publication Date:
Research Org.:
Thomas Jefferson National Accelerator Facility, Newport News, VA (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1089911
Report Number(s):
JLAB-PHY-12-1421; DOE/OR/23177-2690
DOE Contract Number:  
AC05-06OR23177
Resource Type:
Conference
Resource Relation:
Conference: 2012 Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Oct. 27 2012-Nov. 3 2012, Anaheim, CA
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Lee, Seung Joon, Kross, Brian J., McKisson, John E., Weisenberger, Andrew G., Xi, Wenze, Zorn, Carl J., Howell, C. R., Reid, C. D., and Smith, M. P. PhytoPET: Design and initial results of modular PET for plant biology. United States: N. p., 2012. Web. doi:10.1109/NSSMIC.2012.6551323.
Lee, Seung Joon, Kross, Brian J., McKisson, John E., Weisenberger, Andrew G., Xi, Wenze, Zorn, Carl J., Howell, C. R., Reid, C. D., & Smith, M. P. PhytoPET: Design and initial results of modular PET for plant biology. United States. doi:10.1109/NSSMIC.2012.6551323.
Lee, Seung Joon, Kross, Brian J., McKisson, John E., Weisenberger, Andrew G., Xi, Wenze, Zorn, Carl J., Howell, C. R., Reid, C. D., and Smith, M. P. Thu . "PhytoPET: Design and initial results of modular PET for plant biology". United States. doi:10.1109/NSSMIC.2012.6551323.
@article{osti_1089911,
title = {PhytoPET: Design and initial results of modular PET for plant biology},
author = {Lee, Seung Joon and Kross, Brian J. and McKisson, John E. and Weisenberger, Andrew G. and Xi, Wenze and Zorn, Carl J. and Howell, C. R. and Reid, C. D. and Smith, M. P.},
abstractNote = {We have developed a positron emission tomography (PET) system designed specifically for plant imaging in Phytotron at Duke University. Initial evaluation of a PhytoPET system to image the biodistribution of the positron emitting tracer {sup 11}C in live plants is presented. The mechanical arrangement of the detectors is designed to accommodate the unpredictable and random distribution in space of the plant parts such as stems, leaves, and roots. Prototyping such a system requires a completely new PET system design strategy different from preclinical and clinical applications. This PhytoPET design allows flexible arrangements of PET detectors based on individual standalone detector modules built from single 5 cm × 5 cm Hamamatsu H8500 position sensitive photomultiplier tubes. Each H8500 is coupled to a L YSO:Ce scintillator array composed of 48 × 48 elements that are 10 mm thick with a 1 mm pitch. Initial results provide planar PET images from two different arrangements (1 × 4 or 2 × 2) for flexible imaging capability.},
doi = {10.1109/NSSMIC.2012.6551323},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {11}
}

Conference:
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