Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making
Patent
·
OSTI ID:1079245
The present disclosure relates to novel compounds having the structural Formulas (1a,1b), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or pharmaceutically acceptable salt and/or solvate thereof as chemotherapy agents for treating of cancer, particularly androgen-independent prostate cancer. The disclosure also relates to methods for preparing said compounds, and to pharmaceutical compositions comprising said compounds.
- Research Organization:
- US Department of Energy (USDOE), Washington, DC (United States)
- Sponsoring Organization:
- USDOE
- Assignee:
- U.S. Department of Energy (Washington, DC)
- Patent Number(s):
- 8,293,780
- Application Number:
- 13/422,158
- OSTI ID:
- 1079245
- Country of Publication:
- United States
- Language:
- English
Bioisosterism: A Rational Approach in Drug Design
|
journal | January 1996 |
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