Nanoresolution radiology of neurons

Journal Article · Tue May 29 00:00:00 EDT 2012 · Journal of Physics. D, Applied Physics

DOI:https://doi.org/10.1088/0022-3727/45/24/242001· OSTI ID:1057514

Wu, H. R.; Chen, S. T.; Chu, Y. S.; Conley, R.; Bouet, N.; Chien, C. C.; Chen, H. H.; Lin, C. H.; Tung, H. T.; Chen, Y. S.; Margaritondo, G.; Je, J. H.; Hwu, Y.

We report recent advances in hard-x-ray optics—including record spatial resolution—and in staining techniques that enable synchrotron microradiology to produce neurobiology images of quality comparable to electron and visible microscopy. In addition, microradiology offers excellent penetration and effective three-dimensional detection as required for many neuron studies. Our tests include tomographic reconstruction based on projection image sets.

• Research Organization: Brookhaven National Lab. (BNL), Upton, NY (United States)
• Sponsoring Organization: USDOE SC OFFICE OF SCIENCE (SC)
• DOE Contract Number: DE-AC02-98CH10886
• OSTI ID: 1057514
• Report Number(s): BNL-98415-2012-JA; R&D Project: LS001
• Journal Information: Journal of Physics. D, Applied Physics, Vol. 45, Issue 24; ISSN 0022-3727
• Publisher: IOP Publishing
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES