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Title: Thermal effusivity: a promising imaging biomarker to predict radiation-induced skin injuries.

Abstract

An effective screening technology is needed to triage individuals at the time of radiation incidents involving a large population. Three-dimensional thermal tomography is a relatively new development in active thermal imaging technology that produces cross-sectional images based on the subject's ability to transfer heat thermal effusivity at the voxel level. This noninvasive imaging modality has been used successfully in nondestructive examination of complex materials; also it has been shown to predict the severity of radiation-induced skin injuries several days before the manifestation of severe moist desquamations or blister formation symptoms in mice at 40 Gy. If these results are confirmed at lower dose levels in human subjects, a thermal tomography imaging device may be an ideal screening tool in radiation emergencies. This imaging method is non-invasive, relatively simple, easily adaptable for field use, and when properly deployed, it will enhance public emergency preparedness for incidents involving unexpected radiation exposure.

Authors:
; ; ; ;  [1];  [2]
  1. (Nuclear Engineering Division)
  2. (
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1049035
Report Number(s):
ANL/NE/JA-71837
Journal ID: ISSN 0017-9078; TRN: US201217%%301
DOE Contract Number:  
DE-AC02-06CH11357
Resource Type:
Journal Article
Journal Name:
Health Physics
Additional Journal Information:
Journal Volume: 103; Journal Issue: 2; Journal ID: ISSN 0017-9078
Country of Publication:
United States
Language:
ENGLISH
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; BLISTERS; INJURIES; MICE; RADIATIONS; SYMPTOMS; TOMOGRAPHY

Citation Formats

Chu, J. C. H., Templeton, A., Yao, R., Griem, K. L., Sun, J. G., and Rush University). Thermal effusivity: a promising imaging biomarker to predict radiation-induced skin injuries.. United States: N. p., 2012. Web. doi:10.1097/HP.0b013e31824758c2.
Chu, J. C. H., Templeton, A., Yao, R., Griem, K. L., Sun, J. G., & Rush University). Thermal effusivity: a promising imaging biomarker to predict radiation-induced skin injuries.. United States. doi:10.1097/HP.0b013e31824758c2.
Chu, J. C. H., Templeton, A., Yao, R., Griem, K. L., Sun, J. G., and Rush University). Sun . "Thermal effusivity: a promising imaging biomarker to predict radiation-induced skin injuries.". United States. doi:10.1097/HP.0b013e31824758c2.
@article{osti_1049035,
title = {Thermal effusivity: a promising imaging biomarker to predict radiation-induced skin injuries.},
author = {Chu, J. C. H. and Templeton, A. and Yao, R. and Griem, K. L. and Sun, J. G. and Rush University)},
abstractNote = {An effective screening technology is needed to triage individuals at the time of radiation incidents involving a large population. Three-dimensional thermal tomography is a relatively new development in active thermal imaging technology that produces cross-sectional images based on the subject's ability to transfer heat thermal effusivity at the voxel level. This noninvasive imaging modality has been used successfully in nondestructive examination of complex materials; also it has been shown to predict the severity of radiation-induced skin injuries several days before the manifestation of severe moist desquamations or blister formation symptoms in mice at 40 Gy. If these results are confirmed at lower dose levels in human subjects, a thermal tomography imaging device may be an ideal screening tool in radiation emergencies. This imaging method is non-invasive, relatively simple, easily adaptable for field use, and when properly deployed, it will enhance public emergency preparedness for incidents involving unexpected radiation exposure.},
doi = {10.1097/HP.0b013e31824758c2},
journal = {Health Physics},
issn = {0017-9078},
number = 2,
volume = 103,
place = {United States},
year = {2012},
month = {1}
}