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Title: Banded Spherulitic Morphology in Blends of Poly(propylene fumarate) and Poly( -caprolactone) and Interaction with MC3T3-E1 Cells

Journal Article · · Macromolecular Chemistry and physics

The thermal properties, morphological development, crystallization behavior, and miscibility of semicrystalline PCL and its 25, 50, and 75 wt% blends with amorphous PPF in spin-coated thin films crystallized at various crystallization temperatures (T{sub c}) from 25 to 52 C are investigated. The surface roughness of PPF/PCL ({phi}{sub PCL} = 75%) films increases with increasing T{sub c} and consequently the adsorption of serum proteins is also increased. No significant variance is found in surface hydrophilicity or in mouse MC3T3-E1 cell attachment, spreading, and proliferation on PPF/PCL ({phi}{sub PCL} = 75%) films crystallized isothermally at 25, 37, and 45 C, because of low ridge height, nonuniformity in structures, and PPF surface segregation

Research Organization:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Sciences (CNMS)
Sponsoring Organization:
USDOE Office of Science (SC)
DOE Contract Number:
DE-AC05-00OR22725
OSTI ID:
1047638
Journal Information:
Macromolecular Chemistry and physics, Vol. 213, Issue 12; ISSN 1022-1352
Country of Publication:
United States
Language:
English