Biomimetic materials for protein storage and transport
- Elmhurst, IL
- Villa Park, IL
The invention provides a method for the insertion of protein in storage vehicles and the recovery of the proteins from the vehicles, the method comprising supplying isolated protein; mixing the isolated protein with a fluid so as to form a mixture, the fluid comprising saturated phospholipids, lipopolymers, and a surfactant; cycling the mixture between a first temperature and a second temperature; maintaining the mixture as a solid for an indefinite period of time; diluting the mixture in detergent buffer so as to disrupt the composition of the mixture, and diluting to disrupt the fluid in its low viscosity state for removal of the guest molecules by, for example, dialysis, filtering or chromatography dialyzing/filtering the emulsified solid.
- Research Organization:
- US Department of Energy (USDOE), Washington, DC (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- W-31-109-ENG-38
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Number(s):
- 8,168,746
- Application Number:
- 12/148,518
- OSTI ID:
- 1044065
- Country of Publication:
- United States
- Language:
- English
Similar Records
Low molecular weight human pulmonary surfactant protein (SP5): isolation, characterization, and cDNA and amino acid sequences
EFFECTS OF IONIZING RADIATION ON DRUG-PROTEIN BONDS