Signal enhancement using a switchable magnetic trap
- Pleasanton, CA
A system for analyzing a sample including providing a microchannel flow channel; associating the sample with magnetic nanoparticles or magnetic polystyrene-coated beads; moving the sample with said magnetic nanoparticles or magnetic polystyrene-coated beads in the microchannel flow channel; holding the sample with the magnetic nanoparticles or magnetic polystyrene-coated beads in a magnetic trap in the microchannel flow channel; and analyzing the sample obtaining an enhanced analysis signal. An apparatus for analysis of a sample includes magnetic particles connected to the sample, a microchip, a flow channel in the microchip, a source of carrier fluid connected to the flow channel for moving the sample in the flow channel, an electromagnet trap connected to the flow line for selectively magnetically trapping the sample and the magnetic particles, and an analyzer for analyzing the sample.
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC52-07NA27344
- Assignee:
- Lawrence Livermore National Security, LLC. (Livermore, CA)
- Patent Number(s):
- 8,189,186
- Application Number:
- 11/965,598
- OSTI ID:
- 1041249
- Country of Publication:
- United States
- Language:
- English
On-Chip, Real-Time, Single-Copy Polymerase Chain Reaction in Picoliter Droplets
|
journal | November 2007 |
Monodispersed microfluidic droplet generation by shear focusing microfluidic device
|
journal | March 2006 |
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