skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells

Abstract

Yeast cells having an exogenous lactate dehydrogenase gene ae modified by reducing L- or D-lactate:ferricytochrome c oxidoreductase activity in the cell. This leads to reduced consumption of lactate by the cell and can increase overall lactate yields in a fermentation process. Cells having the reduced L- or D-lactate:ferricytochrome c oxidoreductase activity can be screened for by resistance to organic acids such as lactic or glycolic acid.

Inventors:
 [1];  [2];  [3];  [4];  [5];  [6]
  1. Boston, MA
  2. Maple Grove, MN
  3. Highland Ranch, CO
  4. Currie, MN
  5. Camarillo, CA
  6. Minneapolis, MN
Publication Date:
Research Org.:
Cargill Inc. (Wayzata, MN)
Sponsoring Org.:
USDOE
OSTI Identifier:
1039699
Patent Number(s):
8,137,953
Application Number:
12/093,757
Assignee:
Cargill Inc. (Wayzata, MN) GFO
DOE Contract Number:  
FC36-03GO13145
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Miller, Matthew, Suominen, Pirkko, Aristidou, Aristos, Hause, Benjamin Matthew, Van Hoek, Pim, and Dundon, Catherine Asleson. Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells. United States: N. p., 2012. Web.
Miller, Matthew, Suominen, Pirkko, Aristidou, Aristos, Hause, Benjamin Matthew, Van Hoek, Pim, & Dundon, Catherine Asleson. Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells. United States.
Miller, Matthew, Suominen, Pirkko, Aristidou, Aristos, Hause, Benjamin Matthew, Van Hoek, Pim, and Dundon, Catherine Asleson. Tue . "Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells". United States. https://www.osti.gov/servlets/purl/1039699.
@article{osti_1039699,
title = {Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells},
author = {Miller, Matthew and Suominen, Pirkko and Aristidou, Aristos and Hause, Benjamin Matthew and Van Hoek, Pim and Dundon, Catherine Asleson},
abstractNote = {Yeast cells having an exogenous lactate dehydrogenase gene ae modified by reducing L- or D-lactate:ferricytochrome c oxidoreductase activity in the cell. This leads to reduced consumption of lactate by the cell and can increase overall lactate yields in a fermentation process. Cells having the reduced L- or D-lactate:ferricytochrome c oxidoreductase activity can be screened for by resistance to organic acids such as lactic or glycolic acid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {3}
}

Patent:

Save / Share: