Composite material

Hutchens, Stacy A; Woodward, Jonathan; Evans, Barbara R; O'Neill, Hugh M

Title: Composite material

Patent · Tue Feb 07 00:00:00 EST 2012

OSTI ID:1037758

Hutchens, Stacy A ^[1]; Woodward, Jonathan ^[2]; Evans, Barbara R ^[3]; O'Neill, Hugh M ^[1]

Knoxville, TN
Solihull, GB
Oak Ridge, TN

A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC05-00OR22725

Assignee:: UT-Battelle, LLC. (Oak Ridge, TN); University of Tennessee Research Foundation (Knoxville, TN)

Patent Number(s):: 8,110,222

Application Number:: 10/295,461

OSTI ID:: 1037758

Country of Publication:: United States

Language:: English

References (21)

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