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Title: Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins

Patent ·
OSTI ID:1036518

The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-06NA25396
Assignee:
Los Alamos Security, LLC (Los Alamos, NM); Beth Israel Deaconess Medical Center (Boston, MA); Duke University (Durham, NC); The University of Alabama at Birmingham Research Foundation (Birmingham, AL)
Patent Number(s):
8,119,140
Application Number:
11/990,222
OSTI ID:
1036518
Country of Publication:
United States
Language:
English

References (1)

Polygene DNA vaccine induces a high level of protective effect against HIV-vaccinia virus challenge in mice journal September 2004