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Title: Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic Ti-Sb targets

Abstract

The invention provides a method of chemical recovery of no-carrier-added radioactive tin (NCA radiotin) from intermetallide TiSb irradiated with accelerated charged particles. An irradiated sample of TiSb can be dissolved in acidic solutions. Antimony can be removed from the solution by extraction with dibutyl ether. Titanium in the form of peroxide can be separated from tin using chromatography on strong anion-exchange resin. In another embodiment NCA radiotin can be separated from iodide solution containing titanium by extraction with benzene, toluene or chloroform. NCA radiotin can be finally purified from the remaining antimony and other impurities using chromatography on silica gel. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.

Inventors:
 [1];  [1];  [2];  [3];  [3]
  1. Troitsk, RU
  2. Setauket, NY
  3. Obninsk, RU
Publication Date:
Research Org.:
Brookhaven National Lab. (BNL), Upton, NY (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1035033
Patent Number(s):
8,097,064
Application Number:
12/425,038
Assignee:
Brookhaven Science Associates (Upton, NY)
DOE Contract Number:  
AC02-98CH10886
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY

Citation Formats

Lapshina, Elena V, Zhuikov, Boris L, Srivastava, Suresh C, Ermolaev, Stanislav V, and Togaeva, Natalia R. Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic Ti-Sb targets. United States: N. p., 2012. Web.
Lapshina, Elena V, Zhuikov, Boris L, Srivastava, Suresh C, Ermolaev, Stanislav V, & Togaeva, Natalia R. Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic Ti-Sb targets. United States.
Lapshina, Elena V, Zhuikov, Boris L, Srivastava, Suresh C, Ermolaev, Stanislav V, and Togaeva, Natalia R. Tue . "Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic Ti-Sb targets". United States. https://www.osti.gov/servlets/purl/1035033.
@article{osti_1035033,
title = {Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic Ti-Sb targets},
author = {Lapshina, Elena V and Zhuikov, Boris L and Srivastava, Suresh C and Ermolaev, Stanislav V and Togaeva, Natalia R},
abstractNote = {The invention provides a method of chemical recovery of no-carrier-added radioactive tin (NCA radiotin) from intermetallide TiSb irradiated with accelerated charged particles. An irradiated sample of TiSb can be dissolved in acidic solutions. Antimony can be removed from the solution by extraction with dibutyl ether. Titanium in the form of peroxide can be separated from tin using chromatography on strong anion-exchange resin. In another embodiment NCA radiotin can be separated from iodide solution containing titanium by extraction with benzene, toluene or chloroform. NCA radiotin can be finally purified from the remaining antimony and other impurities using chromatography on silica gel. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {1}
}

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