Whole-Genome Sequences of Two Borrelia afzelii and Two Borrelia garinii Lyme Disease Agent Isolates

Journal Article · Thu Dec 01 00:00:00 EST 2011 · Journal of Bacteriology

DOI:https://doi.org/10.1128/JB.05951-11· OSTI ID:1034740

Casjens, S R; Dunn, J; Mongodin, E F; Qiu, W -G; Luft, B J; Fraser-Liggett, C M; Schutzer, S E

Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

• Research Organization: Brookhaven National Lab. (BNL), Upton, NY (United States)
• Sponsoring Organization: NATIONAL INSTITUTE OF HEALTH
• DOE Contract Number: DE-AC02-98CH10886
• OSTI ID: 1034740
• Report Number(s): BNL-96653-2011-JA; JOBAAY; 400412000; TRN: US201204%%159
• Journal Information: Journal of Bacteriology, Vol. 193, Issue 24; ISSN 0021-9193
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
DISEASES
ETIOLOGY
PATHOGENESIS