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U.S. Department of Energy
Office of Scientific and Technical Information

Method of treating depression

Patent ·
OSTI ID:1034635

Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.

Research Organization:
Brookhaven Science Associates, LLC (Upton, NY)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-98CH10886
Assignee:
Brookhaven Science Associates, LLC (Upton, NY)
Patent Number(s):
8,101,600
Application Number:
12/641,968
OSTI ID:
1034635
Country of Publication:
United States
Language:
English

References (1)

Effect of potassium channel modulators in mouse forced swimming test journal April 1999

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