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Title: Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins

Abstract

The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.

Inventors:
 [1];  [1];  [2];  [3];  [3];  [3];  [4];  [5];  [6]
  1. Durham, NC
  2. Los Alamos, NM
  3. Birmingham, AL
  4. Hoover, AL
  5. Alabaster, AL
  6. Chapel Hill, NC
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1034345
Patent Number(s):
8,071,107
Application Number:
10/572,638
Assignee:
Duke University (Durham, NC); The Regents of the University of California (Oakland, CA); The University of Alabama at Birmingham Research Foundation (Birmingham, AL) LANL
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Haynes, Barton F, Gao, Feng, Korber, Bette T, Hahn, Beatrice H, Shaw, George M, Kothe, Denise, Li, Ying Ying, Decker, Julie, and Liao, Hua-Xin. Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins. United States: N. p., 2011. Web.
Haynes, Barton F, Gao, Feng, Korber, Bette T, Hahn, Beatrice H, Shaw, George M, Kothe, Denise, Li, Ying Ying, Decker, Julie, & Liao, Hua-Xin. Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins. United States.
Haynes, Barton F, Gao, Feng, Korber, Bette T, Hahn, Beatrice H, Shaw, George M, Kothe, Denise, Li, Ying Ying, Decker, Julie, and Liao, Hua-Xin. Tue . "Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins". United States. https://www.osti.gov/servlets/purl/1034345.
@article{osti_1034345,
title = {Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins},
author = {Haynes, Barton F and Gao, Feng and Korber, Bette T and Hahn, Beatrice H and Shaw, George M and Kothe, Denise and Li, Ying Ying and Decker, Julie and Liao, Hua-Xin},
abstractNote = {The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {12}
}

Patent:

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