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Title: Combining Transmission Geometry Laser Ablation and a Non Contact Continuous Flow Surface Sampling Probe/Electrospray Emitter for Mass Spectrometry-Based Chemical Imaging

Abstract

This paper describes the coupling of ambient pressure transmission geometry laser ablation with a liquid phase sample collection into a continuous flow surface sampling probe/electrospray emitter for mass spectrometry based chemical imaging. The flow probe/emitter device was placed in close proximity to the surface to collect the sample plume produced by laser ablation. The sample collected was immediately aspirated into the probe and on to the electrospray emitter, ionized and detected with the mass spectrometer. Freehand drawn ink lines and letters and an inked fingerprint on microscope slides were analyzed. The circular laser ablation area was about 210 m in diameter and under the conditions used in these experiments the spatial resolution, as determined by the size of the surface features distinguished in the chemical images, was about 100 m.

Authors:
 [1];  [1];  [1]
  1. ORNL
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1032812
DOE Contract Number:  
DE-AC05-00OR22725
Resource Type:
Journal Article
Journal Name:
Rapid Communications in Mass Spectrometry
Additional Journal Information:
Journal Volume: 25; Journal Issue: 24; Journal ID: ISSN 0951-4198
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ABLATION; GEOMETRY; LASERS; MASS SPECTROMETERS; MASS SPECTROSCOPY; MICROSCOPES; PLUMES; PROBES; SAMPLING; SPATIAL RESOLUTION; Laser Ablation/Surface Sampling Probe Chemical Imaging

Citation Formats

Ovchinnikova, Olga S, Kertesz, Vilmos, and Van Berkel, Gary J. Combining Transmission Geometry Laser Ablation and a Non Contact Continuous Flow Surface Sampling Probe/Electrospray Emitter for Mass Spectrometry-Based Chemical Imaging. United States: N. p., 2011. Web. doi:10.1002/rcm.5285.
Ovchinnikova, Olga S, Kertesz, Vilmos, & Van Berkel, Gary J. Combining Transmission Geometry Laser Ablation and a Non Contact Continuous Flow Surface Sampling Probe/Electrospray Emitter for Mass Spectrometry-Based Chemical Imaging. United States. doi:10.1002/rcm.5285.
Ovchinnikova, Olga S, Kertesz, Vilmos, and Van Berkel, Gary J. Sat . "Combining Transmission Geometry Laser Ablation and a Non Contact Continuous Flow Surface Sampling Probe/Electrospray Emitter for Mass Spectrometry-Based Chemical Imaging". United States. doi:10.1002/rcm.5285.
@article{osti_1032812,
title = {Combining Transmission Geometry Laser Ablation and a Non Contact Continuous Flow Surface Sampling Probe/Electrospray Emitter for Mass Spectrometry-Based Chemical Imaging},
author = {Ovchinnikova, Olga S and Kertesz, Vilmos and Van Berkel, Gary J},
abstractNote = {This paper describes the coupling of ambient pressure transmission geometry laser ablation with a liquid phase sample collection into a continuous flow surface sampling probe/electrospray emitter for mass spectrometry based chemical imaging. The flow probe/emitter device was placed in close proximity to the surface to collect the sample plume produced by laser ablation. The sample collected was immediately aspirated into the probe and on to the electrospray emitter, ionized and detected with the mass spectrometer. Freehand drawn ink lines and letters and an inked fingerprint on microscope slides were analyzed. The circular laser ablation area was about 210 m in diameter and under the conditions used in these experiments the spatial resolution, as determined by the size of the surface features distinguished in the chemical images, was about 100 m.},
doi = {10.1002/rcm.5285},
journal = {Rapid Communications in Mass Spectrometry},
issn = {0951-4198},
number = 24,
volume = 25,
place = {United States},
year = {2011},
month = {1}
}