Systems for the expression of orthogonal translation components in eubacterial host cells

Ryu, Youngha; Schultz, Peter G

Systems for the expression of orthogonal translation components in eubacterial host cells

Patent · 14 June 2011

OSTI ID:1021889

Ryu, Youngha ^[1]; Schultz, Peter G ^[2]

San Diego, CA
La Jolla, CA

The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.

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Research Organization:: The Scripps Research Institute (La Jolla, CA)

Sponsoring Organization:: USDOE

DOE Contract Number:: FG02-03ER46051

Assignee:: The Scripps Research Institute (La Jolla, CA)

Patent Number(s):: 7,960,141

Application Number:: 11/715,672

OSTI ID:: 1021889

Country of Publication:: United States

Language:: English

References (17)

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