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Title: Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy

Abstract

There is provided a method and device for remote sampling, preparation and optical interrogation of a sample using light scattering and light absorption methods. The portable device is a filtration-based device that removes interfering background particle material from the sample matrix by segregating or filtering the chosen analyte from the sample solution or matrix while allowing the interfering background particles to be pumped out of the device. The segregated analyte is then suspended in a diluent for analysis. The device is capable of calculating an initial concentration of the analyte, as well as diluting the analyte such that reliable optical measurements can be made. Suitable analytes include cells, microorganisms, bioparticles, pathogens and diseases. Sample matrixes include biological fluids such as blood and urine, as well as environmental samples including waste water.

Inventors:
 [1];  [2];  [3];  [4];  [1];  [5];  [1]
  1. Los Alamos, NM
  2. Barranquilla, CO
  3. Fort Walton Beach, FL
  4. Santa Fe, NM
  5. Temple Terrace, FL
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1019396
Patent Number(s):
7,986,399
Application Number:
US Patent Application 11/877,136
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM) LANL
DOE Contract Number:
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Stark, Peter C, Zurek, Eduardo, Wheat, Jeffrey V, Dunbar, John M, Olivares, Jose A, Garcia-Rubio, Luis H, and Ward, Michael D. Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy. United States: N. p., 2011. Web.
Stark, Peter C, Zurek, Eduardo, Wheat, Jeffrey V, Dunbar, John M, Olivares, Jose A, Garcia-Rubio, Luis H, & Ward, Michael D. Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy. United States.
Stark, Peter C, Zurek, Eduardo, Wheat, Jeffrey V, Dunbar, John M, Olivares, Jose A, Garcia-Rubio, Luis H, and Ward, Michael D. Tue . "Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy". United States. doi:. https://www.osti.gov/servlets/purl/1019396.
@article{osti_1019396,
title = {Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy},
author = {Stark, Peter C and Zurek, Eduardo and Wheat, Jeffrey V and Dunbar, John M and Olivares, Jose A and Garcia-Rubio, Luis H and Ward, Michael D},
abstractNote = {There is provided a method and device for remote sampling, preparation and optical interrogation of a sample using light scattering and light absorption methods. The portable device is a filtration-based device that removes interfering background particle material from the sample matrix by segregating or filtering the chosen analyte from the sample solution or matrix while allowing the interfering background particles to be pumped out of the device. The segregated analyte is then suspended in a diluent for analysis. The device is capable of calculating an initial concentration of the analyte, as well as diluting the analyte such that reliable optical measurements can be made. Suitable analytes include cells, microorganisms, bioparticles, pathogens and diseases. Sample matrixes include biological fluids such as blood and urine, as well as environmental samples including waste water.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 26 00:00:00 EDT 2011},
month = {Tue Jul 26 00:00:00 EDT 2011}
}

Patent:

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