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Title: High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

Abstract

This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

Inventors:
 [1];  [2];  [3];  [4];  [1]
  1. (Livermore, CA)
  2. (Davis, CA)
  3. (Sacramento, CA)
  4. (Pasedena, CA)
Publication Date:
Research Org.:
Lawrence Livermore National Security, LLC (Livermore, CA); University of California (Oakland, CA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1014691
Patent Number(s):
7,791,734
Application Number:
US Patent Application 11/417,074
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA); University of California (Oakland, CA) LLNL
DOE Contract Number:  
W-7405ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Olivier, Scot S., Werner, John S., Zawadzki, Robert J., Laut, Sophie P., and Jones, Steven M. High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography. United States: N. p., 2010. Web.
Olivier, Scot S., Werner, John S., Zawadzki, Robert J., Laut, Sophie P., & Jones, Steven M. High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography. United States.
Olivier, Scot S., Werner, John S., Zawadzki, Robert J., Laut, Sophie P., and Jones, Steven M. Tue . "High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography". United States. doi:. https://www.osti.gov/servlets/purl/1014691.
@article{osti_1014691,
title = {High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography},
author = {Olivier, Scot S. and Werner, John S. and Zawadzki, Robert J. and Laut, Sophie P. and Jones, Steven M.},
abstractNote = {This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 07 00:00:00 EDT 2010},
month = {Tue Sep 07 00:00:00 EDT 2010}
}

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