D-erythroascorbic acid: Its preparations, chemistry, and metabolism (fungi and plants). Final report
- Washington State Univ., Pullman, WA (United States). Inst. of Biological Chemistry
- Kansas State Univ., Manhattan, KS (United States). Dept. of Grain Science and Industry
The origin of oxalate in plants has received considerable attention and glycolate metabolism has been generally regarded as a prime precursor candidate although studies on the metabolism of L-ascorbic acid single out that plant constituent as well. Experiments with oxalate-accumulating plants that contain little or no tartaric acid revealed the presence of a comparable L-ascorbic acid metabolism with the exception that the cleavage products were oxalic acid and L-threonic acid or products of L-threonic acid metabolism. A reasonable mechanism for cleavage of L-ascorbic acid at the endiolic bond is found in studies on the photooxygenation of L-ascorbic acid. Presumably, analogs of L-ascorbic acid that differ only in the substituent at C4 also form a hydroperoxide in the presence of alkaline hydrogen peroxide and subsequently yield oxalic acid and the corresponding aldonic acid or its lactone. We became interested in such a possibility when we discovered that L-ascorbic acid was rare or absent in certain yeasts and fungi whereas a L-ascorbic acid analog, D-glycero-pent-2-enono- 1,4-lactone (D-erythroascorbic acid), was present. It has long been known that oxalate occurs in yeasts and fungi and its production plays a role in plant pathogenesis. As to the biosynthetic origin of fungal oxalic acid there is little information although it is generally assumed that oxaloacetate or possibly, glycolate, might be that precursor.
- Research Organization:
- Washington State Univ., Pullman, WA (United States). Inst. of Biological Chemistry; Kansas State Univ., Manhattan, KS (United States). Dept. of Grain Science and Industry
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG06-88ER13890
- OSTI ID:
- 10131033
- Report Number(s):
- DOE/ER/13890-T1; ON: DE93008916
- Resource Relation:
- Other Information: PBD: [1991]
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
MONOSACCHARIDES
CHEMICAL PREPARATION
LABELLING
METABOLITES
PROGRESS REPORT
LABELLED COMPOUNDS
FUNGI
CARBON 14 COMPOUNDS
TRITIUM COMPOUNDS
LACTONES
BIOLOGICAL PATHWAYS
OXALIC ACID
ASCORBIC ACID
550501
400201
TRACER TECHNIQUES
CHEMICAL AND PHYSICOCHEMICAL PROPERTIES