Method for analyzing microbial communities

Zhou, Jizhong; Wu, Liyou

Method for analyzing microbial communities

Patent · 20 July 2010

OSTI ID:1012821

Zhou, Jizhong ^[1]; Wu, Liyou ^[1]

Oak Ridge, TN

The present invention provides a method for quantitatively analyzing microbial genes, species, or strains in a sample that contains at least two species or strains of microorganisms. The method involves using an isothermal DNA polymerase to randomly and representatively amplify genomic DNA of the microorganisms in the sample, hybridizing the resultant polynucleotide amplification product to a polynucleotide microarray that can differentiate different genes, species, or strains of microorganisms of interest, and measuring hybridization signals on the microarray to quantify the genes, species, or strains of interest.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC05-00OR22725

Assignee:: UT-Battelle, LLC (Oak Ridge, TN)

Patent Number(s):: 7,759,057

Application Number:: 10/943,067

OSTI ID:: 1012821

Country of Publication:: United States

Language:: English

References (17)

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