Cryogenic immersion microscope

Title: Cryogenic immersion microscope

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Abstract

A cryogenic immersion microscope whose objective lens is at least partially in contact with a liquid reservoir of a cryogenic liquid, in which reservoir a sample of interest is immersed is disclosed. When the cryogenic liquid has an index of refraction that reduces refraction at interfaces between the lens and the sample, overall resolution and image quality are improved. A combination of an immersion microscope and x-ray microscope, suitable for imaging at cryogenic temperatures is also disclosed.

Inventors:

Le Gros, Mark ^[1]; Larabell, Carolyn A ^[1]

Berkeley, CA

Publication Date:: 2010-12-14

Research Org.:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1009534

Patent Number(s):: 7,852,554

Application Number:: 11/911,957

Assignee:: The Regents of the University of California (Oakland, CA)

DOE Contract Number:: AC03-76SF00098

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Citation Formats


                    Le Gros, Mark, and Larabell, Carolyn A. Cryogenic immersion microscope.  United States: N. p., 2010. 
        Web.

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                    Le Gros, Mark, & Larabell, Carolyn A. Cryogenic immersion microscope.  United States.

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                    Le Gros, Mark, and Larabell, Carolyn A. Tue .  
        "Cryogenic immersion microscope".  United States.  https://www.osti.gov/servlets/purl/1009534.

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@article{osti_1009534,

  title        = {Cryogenic immersion microscope},

  author       = {Le Gros, Mark and Larabell, Carolyn A},

  abstractNote = {A cryogenic immersion microscope whose objective lens is at least partially in contact with a liquid reservoir of a cryogenic liquid, in which reservoir a sample of interest is immersed is disclosed. When the cryogenic liquid has an index of refraction that reduces refraction at interfaces between the lens and the sample, overall resolution and image quality are improved. A combination of an immersion microscope and x-ray microscope, suitable for imaging at cryogenic temperatures is also disclosed.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/1009534},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2010},

  month        = {12}

}

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