SIBYLS - A SAXS and protein crystallography beamline at the ALS

Trame, Christine; MacDowell, Alastair A; Celestre, Richard S; Padmore, Howard A; Cambie, Daniella; Domning, Edward E; Duarte, Robert M; Kelez, Nicholas; Plate, David W; Holton, James M; Frankel, Kenneth; Tsutakawa, Susan; Tsuruta, Hiro; Tainer, John A; Cooper, Priscilla K

Title: SIBYLS - A SAXS and protein crystallography beamline at the ALS

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Abstract

The new Structurally Integrated BiologY for Life Sciences (SIBYLS) beamline at the Advanced Light Source will be dedicated to Macromolecular Crystallography (PX) and Small Angle X-ray Scattering (SAXS). SAXS will provide structural information of macromolecules in solutions and will complement high resolution PX studies on the same systems but in a crystalline state. The x-ray source is one of the 5 Tesla superbend dipoles recently installed at the ALS that allows for a hard x-ray program to be developed on the relatively low energy Advanced Light Source (ALS) ring (1.9 GeV). The beamline is equipped with fast interchangeable monochromator elements, consisting of either a pair of single Si(111) crystals for crystallography, or a pair of multilayers for the SAXS mode data collection (E/{Delta}E {approx} 1/110). Flux rates with Si(111) crystals for PX are measured as 2 x 10{sup 11} hv/sec/400 mA through a 100 {micro}m pinhole at 12.4 KeV. For SAXS the flux is up to 3 x 10{sup 13} photons/sec at 10 KeV with all apertures open when using the multilayer monochromator elements. The performance characteristics of this unique beamline will be described.

Authors:: Trame, Christine; MacDowell, Alastair A; Celestre, Richard S; Padmore, Howard A; Cambie, Daniella; Domning, Edward E; Duarte, Robert M; Kelez, Nicholas; Plate, David W; Holton, James M; Frankel, Kenneth; Tsutakawa, Susan; Tsuruta, Hiro; Tainer, John A; Cooper, Priscilla K

Publication Date:: Fri Aug 22 00:00:00 EDT 2003

Research Org.:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Sponsoring Org.:: USDOE Director. Office of Science. Basic Energy Sciences Contract No. DE-AC03-76SF00098; NIH Grant CA92584-04 (US)

OSTI Identifier:: 817640

Report Number(s):: LBNL-53767
R&D Project: 458080; TRN: US0305222

DOE Contract Number:: AC03-76SF00098

Resource Type:: Conference

Resource Relation:: Conference: Eight International Conference on Synchrotron Radiation Instrumentation, San Francisco, CA (US), 08/25/2003--08/29/2003; Other Information: PBD: 22 Aug 2003

Country of Publication:: United States

Language:: English

Subject:: 43 PARTICLE ACCELERATORS; 47 OTHER INSTRUMENTATION; ADVANCED LIGHT SOURCE; APERTURES; BIOLOGY; CRYSTALLOGRAPHY; DIPOLES; MONOCHROMATORS; PERFORMANCE; PROTEINS; RESOLUTION; SCATTERING; SYNCHROTRON RADIATION; X-RAY SOURCES; PROTEIN CRYSTALLOGRAPHY SMALL ANGLE SCATTERING BEAMLINE X-RAYS

Citation Formats


                    Trame, Christine, MacDowell, Alastair A, Celestre, Richard S, Padmore, Howard A, Cambie, Daniella, Domning, Edward E, Duarte, Robert M, Kelez, Nicholas, Plate, David W, Holton, James M, Frankel, Kenneth, Tsutakawa, Susan, Tsuruta, Hiro, Tainer, John A, and Cooper, Priscilla K. SIBYLS - A SAXS and protein crystallography beamline at the ALS.  United States: N. p., 2003. 
        Web.

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                    Trame, Christine, MacDowell, Alastair A, Celestre, Richard S, Padmore, Howard A, Cambie, Daniella, Domning, Edward E, Duarte, Robert M, Kelez, Nicholas, Plate, David W, Holton, James M, Frankel, Kenneth, Tsutakawa, Susan, Tsuruta, Hiro, Tainer, John A, & Cooper, Priscilla K. SIBYLS - A SAXS and protein crystallography beamline at the ALS.  United States.

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                    Trame, Christine, MacDowell, Alastair A, Celestre, Richard S, Padmore, Howard A, Cambie, Daniella, Domning, Edward E, Duarte, Robert M, Kelez, Nicholas, Plate, David W, Holton, James M, Frankel, Kenneth, Tsutakawa, Susan, Tsuruta, Hiro, Tainer, John A, and Cooper, Priscilla K. 2003.  
        "SIBYLS - A SAXS and protein crystallography beamline at the ALS".  United States.  https://www.osti.gov/servlets/purl/817640.

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@article{osti_817640,

  title        = {SIBYLS - A SAXS and protein crystallography beamline at the ALS},

  author       = {Trame, Christine and MacDowell, Alastair A and Celestre, Richard S and Padmore, Howard A and Cambie, Daniella and Domning, Edward E and Duarte, Robert M and Kelez, Nicholas and Plate, David W and Holton, James M and Frankel, Kenneth and Tsutakawa, Susan and Tsuruta, Hiro and Tainer, John A and Cooper, Priscilla K},

  abstractNote = {The new Structurally Integrated BiologY for Life Sciences (SIBYLS) beamline at the Advanced Light Source will be dedicated to Macromolecular Crystallography (PX) and Small Angle X-ray Scattering (SAXS). SAXS will provide structural information of macromolecules in solutions and will complement high resolution PX studies on the same systems but in a crystalline state. The x-ray source is one of the 5 Tesla superbend dipoles recently installed at the ALS that allows for a hard x-ray program to be developed on the relatively low energy Advanced Light Source (ALS) ring (1.9 GeV). The beamline is equipped with fast interchangeable monochromator elements, consisting of either a pair of single Si(111) crystals for crystallography, or a pair of multilayers for the SAXS mode data collection (E/{Delta}E {approx} 1/110). Flux rates with Si(111) crystals for PX are measured as 2 x 10{sup 11} hv/sec/400 mA through a 100 {micro}m pinhole at 12.4 KeV. For SAXS the flux is up to 3 x 10{sup 13} photons/sec at 10 KeV with all apertures open when using the multilayer monochromator elements. The performance characteristics of this unique beamline will be described.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/817640},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Fri Aug 22 00:00:00 EDT 2003},

  month        = {Fri Aug 22 00:00:00 EDT 2003}

}

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