Comparative mutagenesis of human cells in vivo and in vitro

Technical Report · Fri May 01 00:00:00 EDT 1992

DOI:https://doi.org/10.2172/5115937· OSTI ID:5115937

Thilly, W G

This report discusses measuring methods of point mutations; high density cell cultures for low dose studies; measurement and sequence determination of mutations in DNA; the mutational spectra of styrene oxide and ethlyene oxide in TK-6 cells; mutational spectrum of Cr in human lymphoblast cells; mutational spectra of radon in TK-6 cells; and the mutational spectra of smokeless tobacco. (CBS)

• Research Organization: Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: FG02-86ER60448
• OSTI ID: 5115937
• Report Number(s): DOE/ER/60448-T3; ON: DE92015177
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GENE MUTATIONS
MEASURING METHODS
MUTAGENESIS
ORGANIC COMPOUNDS
BIOLOGICAL EFFECTS
OXIDES
STYRENE
BIOLOGICAL RADIATION EFFECTS
CULTURE MEDIA
DNA SEQUENCING
GENOTYPE
HUMAN POPULATIONS
IN VITRO
IN VIVO
MITOCHONDRIA
SEPARATION PROCESSES
ALKYLATED AROMATICS
AROMATICS
CELL CONSTITUENTS
CHALCOGENIDES
HYDROCARBONS
MUTATIONS
OXYGEN COMPOUNDS
POPULATIONS
RADIATION EFFECTS
STRUCTURAL CHEMICAL ANALYSIS
550400* - Genetics
560300 - Chemicals Metabolism & Toxicology
560120 - Radiation Effects on Biochemicals
Cells
& Tissue Culture