Three immobilized-cell columnar bioreactors for enhanced production of commodity chemicals

Conference · Thu Jul 01 00:00:00 EDT 1993

OSTI ID:10176276

Davison, B H; Scott, C D; Kaufman, E N

Immobilized-cell fluidized-bed bioreactors (FBRS) can be used with a variety of fermentations to increase production of fuels, solvents, organic acids, and other fermentation products. Part of the increased rates and yields are due to the immobilization of the biocatalyst at high concentrations. This FBR system with immobilized Zymomonas mobiles increased ethanol productivity more than tenfold with 99% conversion and near stoichiometric yields. FBRs also offer several additional modes of operation for simultaneous fermentation and separation to further increase production by removing the inhibitory products directly from the continuous fermentation. The production of lactic acid by immobilized Lactobacillus was augmented with the addition and removal of solid adsorbent particles to the FBR. An immiscible organic extractant also was used to extract butanol from the acetone-butanol fermentation by Clostridium acetobutylicum. Demonstrations with these FBR systems have already shown definite advantages by improved overall product yields (decreasing feed costs) and by increased rates (decreasing capital and operating costs). Further demonstration and scale-up continue.

• Research Organization: Oak Ridge National Lab., TN (United States)
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: AC05-84OR21400
• OSTI ID: 10176276
• Report Number(s): CONF-9308106-1; ON: DE93017759
• Resource Relation: Conference: 1. biomass conference of the Americas: energy, environment, agriculture, and industry,Burlington, VT (United States),30 Aug - 2 Sep 1993; Other Information: PBD: [1993]
• Country of Publication: United States
• Language: English

Related Subjects

10 SYNTHETIC FUELS
59 BASIC BIOLOGICAL SCIENCES
32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATION
BIOREACTORS
PERFORMANCE
ZYMOMONAS MOBILIS
LACTOBACILLUS
CLOSTRIDIUM ACETOBUTYLICUM
FERMENTATION
SOLVENTS
FUELS
ORGANIC ACIDS
CATALYSTS
ETHANOL FUELS
SYNTHESIS
LACTIC ACID
BUTANOLS
CHEMICAL INDUSTRY
100200
550200
320303
PRODUCTION
BIOCHEMISTRY
EQUIPMENT AND PROCESSES