Laue diffraction protein crystallography at the National Synchrotron Light Source
- Scripps Institution of Oceanography, La Jolla, CA (United States)
- Brookhaven National Lab., Upton, NY (United States)
- Chicago Univ., IL (United States)
- Argonne National Lab., IL (United States)
A new facility for the study of protein crystal structure using Laue diffraction has been established at the X26 beam line of the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory. The characteristics of the beam line and diffraction apparatus are described. Selected results of some of the initial experiments are discussed briefly by beam line users to illustrate the scope of the experimental program. Because the Laue method permits the recording of large data sets in a single shot, one goal in establishing this facility has been to develop the means to study time-resolved structures within protein crystals. Systems being studied include: the reactions catalyzed by trypsin; photolysis of carbonmonoxy myoglobin; and the photocycle of photoactive yellow protein.
- Research Organization:
- Brookhaven National Lab., Upton, NY (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States); Department of Health and Human Services, Washington, DC (United States); Keck Foundation (United States)
- DOE Contract Number:
- AC02-76CH00016; W-31109-ENG-38
- OSTI ID:
- 10142364
- Report Number(s):
- BNL-48531; CONF-921116-23; ON: DE93009537; CNN: Grant GM44292; Grant GM36452; Grant GM37684
- Resource Relation:
- Conference: 12. international conference on the application of accelerators in research and industry,Denton, TX (United States),2-5 Nov 1992; Other Information: PBD: [1992]
- Country of Publication:
- United States
- Language:
- English
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