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Title: DE-FG02-04ER63746 FinalTechnicalReport

Technical Report ·
DOI:https://doi.org/10.2172/963660· OSTI ID:963660

This is the final technical report for a project involving the study of stress response systems in the radiation-resistant bacterium, Deinococcus radiodurans. Three stresses of importance for a mixed waste treatment strain were studied, heat shock, solvent shock, and phosphate starvation. In each case, specific genes involved in the ability to survive the stress were identified using a systems biology approach, and analysis of mutants was used to understand mechanisms. This study has led to increased understanding of the ways in which a potential treatment strain could be manipulated to survive multiple stresses for treatment of mixed wastes.

Research Organization:
Univ. of Washington, Seattle, WA (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
DOE Contract Number:
FG02-04ER63746
OSTI ID:
963660
Report Number(s):
DOE ER63746-1; TRN: US201001%%578
Country of Publication:
United States
Language:
English