Subgenomic HCV RNA decline during interferon-a treatment is biphasic and dose dependent
Conference
·
OSTI ID:957713
- Los Alamos National Laboratory
- UNIV OF ILLINOIS
Although replicon systems have been extensively used to investigate interferon-{alpha} (IFN) treatment a detailed description of genotype -1 b-HCV -sub-genomic replicon (sg 1 b) kinetics in the presence of IFN is still missing. Here, we sought to analyze sg 1 b under various IFN concentrations and define its decay patterns.
- Research Organization:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC52-06NA25396
- OSTI ID:
- 957713
- Report Number(s):
- LA-UR-08-04254; LA-UR-08-4254; TRN: US201016%%125
- Resource Relation:
- Conference: 15th International Symposium on HCV ; October 5, 2008 ; San Antonio, TX
- Country of Publication:
- United States
- Language:
- English
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