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Title: Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications

Abstract

Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 nm and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (>_ 20 nm) are difficult to purify by other means, and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.

Authors:
; ; ; ; ;
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
Materials Sciences Division
OSTI Identifier:
927872
Report Number(s):
LBNL-194E
TRN: US200816%%1105
DOE Contract Number:  
DE-AC02-05CH11231
Resource Type:
Journal Article
Journal Name:
Nano Letters
Additional Journal Information:
Journal Volume: 8; Journal Issue: 4; Related Information: Journal Publication Date: April 2008
Country of Publication:
United States
Language:
English
Subject:
36; DNA; GOLD; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; PLASMONS; SUBSTRATES; GOLD, NANOPARTICLE, NANOCRYSTAL, PLASMON, DNA, HPLC, ANION-EXCHANGE, BIOCONJUGATE, SELF-ASSEMBLY

Citation Formats

Alivisatos, Paul, Claridge, Shelley A, Liang, Huiyang W, Basu, Sourav Roger, Frechet, Jean M.J., and Alivisatos, A Paul. Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications. United States: N. p., 2008. Web.
Alivisatos, Paul, Claridge, Shelley A, Liang, Huiyang W, Basu, Sourav Roger, Frechet, Jean M.J., & Alivisatos, A Paul. Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications. United States.
Alivisatos, Paul, Claridge, Shelley A, Liang, Huiyang W, Basu, Sourav Roger, Frechet, Jean M.J., and Alivisatos, A Paul. 2008. "Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications". United States. https://www.osti.gov/servlets/purl/927872.
@article{osti_927872,
title = {Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications},
author = {Alivisatos, Paul and Claridge, Shelley A and Liang, Huiyang W and Basu, Sourav Roger and Frechet, Jean M.J. and Alivisatos, A Paul},
abstractNote = {Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 nm and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (>_ 20 nm) are difficult to purify by other means, and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.},
doi = {},
url = {https://www.osti.gov/biblio/927872}, journal = {Nano Letters},
number = 4,
volume = 8,
place = {United States},
year = {Fri Apr 11 00:00:00 EDT 2008},
month = {Fri Apr 11 00:00:00 EDT 2008}
}