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Title: Optimization of screening for radioactivity in urine by liquid scintillation.

Abstract

Numerous events have or could have resulted in the inadvertent uptake of radionuclides by fairly large populations. Should a population receive an uptake, valuable information could be obtained by using liquid scintillation counting (LSC) techniques to quickly screen urine from a sample of the affected population. This study investigates such LSC parameters as discrimination, quench, volume, and count time to yield guidelines for analyzing urine in an emergency situation. Through analyzing variations of the volume and their relationships to the minimum detectable activity (MDA), the optimum ratio of sample size to scintillating chemical cocktail was found to be 1:3. Using this optimum volume size, the alpha MDA varied from 2100 pCi/L for a 30-second count time to 35 pCi/L for a 1000-minute count time. The typical count time used by the Sandia National Laboratories Radiation Protection Sample Diagnostics program is 30 minutes, which yields an alpha MDA of 200 pCi/L. Because MDA is inversely proportional to the square root of the count time, count time can be reduced in an emergency situation to achieve the desired MDA or response time. Note that approximately 25% of the response time is used to prepare the samples and complete the associated paperwork. Itmore » was also found that if the nuclide of interest is an unknown, pregenerated discriminator settings and efficiency calibrations can be used to produce an activity value within a factor of two, which is acceptable for a screening method.« less

Authors:
; ;  [1]
  1. Technadyne Engineering Consultants, Inc., Albuquerque, NM
Publication Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
920786
Report Number(s):
SAND2007-5312
TRN: US0800939
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; URINE; LIQUID SCINTILLATION DETECTORS; SCINTILLATION COUNTING; EMERGENCY PLANS; RECOMMENDATIONS; Radiation victims; United States.; Scintillation counters.; Radiation-Dosage-Reporting.; Liquid scintillation counting.; Radiation dosimetry.; Medical screening.

Citation Formats

Shanks, Sonoya Toyoko, Reese, Robert P, and Preston, Rose T. Optimization of screening for radioactivity in urine by liquid scintillation.. United States: N. p., 2007. Web. doi:10.2172/920786.
Shanks, Sonoya Toyoko, Reese, Robert P, & Preston, Rose T. Optimization of screening for radioactivity in urine by liquid scintillation.. United States. https://doi.org/10.2172/920786
Shanks, Sonoya Toyoko, Reese, Robert P, and Preston, Rose T. 2007. "Optimization of screening for radioactivity in urine by liquid scintillation.". United States. https://doi.org/10.2172/920786. https://www.osti.gov/servlets/purl/920786.
@article{osti_920786,
title = {Optimization of screening for radioactivity in urine by liquid scintillation.},
author = {Shanks, Sonoya Toyoko and Reese, Robert P and Preston, Rose T},
abstractNote = {Numerous events have or could have resulted in the inadvertent uptake of radionuclides by fairly large populations. Should a population receive an uptake, valuable information could be obtained by using liquid scintillation counting (LSC) techniques to quickly screen urine from a sample of the affected population. This study investigates such LSC parameters as discrimination, quench, volume, and count time to yield guidelines for analyzing urine in an emergency situation. Through analyzing variations of the volume and their relationships to the minimum detectable activity (MDA), the optimum ratio of sample size to scintillating chemical cocktail was found to be 1:3. Using this optimum volume size, the alpha MDA varied from 2100 pCi/L for a 30-second count time to 35 pCi/L for a 1000-minute count time. The typical count time used by the Sandia National Laboratories Radiation Protection Sample Diagnostics program is 30 minutes, which yields an alpha MDA of 200 pCi/L. Because MDA is inversely proportional to the square root of the count time, count time can be reduced in an emergency situation to achieve the desired MDA or response time. Note that approximately 25% of the response time is used to prepare the samples and complete the associated paperwork. It was also found that if the nuclide of interest is an unknown, pregenerated discriminator settings and efficiency calibrations can be used to produce an activity value within a factor of two, which is acceptable for a screening method.},
doi = {10.2172/920786},
url = {https://www.osti.gov/biblio/920786}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Aug 01 00:00:00 EDT 2007},
month = {Wed Aug 01 00:00:00 EDT 2007}
}